TitleDatePubMed ID
Establishment of a novel triple-transgenic mouse: conditionally and liver-specifically expressing hepatitis C virus NS3/4A protease.2014 Nov25200433
Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease.2014 Sep 1525155387
Key binding and susceptibility of NS3/4A serine protease inhibitors against hepatitis C virus.2014 Apr 2824689657
Ligand bioactive conformation plays a critical role in the design of drugs that target the hepatitis C virus NS3 protease.2014 Mar 1324144444
Cleavage of the T cell protein tyrosine phosphatase by the hepatitis C virus nonstructural 3/4A protease induces a Th1 to Th2 shift reversible by ribavirin therapy.2014 Feb 1524442435
Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease.2014 Feb23929719
Novel, sulfonamide linked inhibitors of the hepatitis C virus NS3 protease.2014 Feb 124405705
A 3D structural model and dynamics of hepatitis C virus NS3/4A protease (genotype 4a, strain ED43) suggest conformational instability of the catalytic triad: implications in catalysis and drug resistivity.201423768174
In vitro phenotypic characterization of hepatitis C virus NS3 protease variants observed in clinical studies of telaprevir.2013 Dec24100495
Azetidines and spiro azetidines as novel P2 units in hepatitis C virus NS3 protease inhibitors.2013 Dec 124135727