Title | Date | PubMed ID |
Establishment of a novel triple-transgenic mouse: conditionally and liver-specifically expressing hepatitis C virus NS3/4A protease. | 2014 Nov | 25200433 |
Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease. | 2014 Sep 15 | 25155387 |
Key binding and susceptibility of NS3/4A serine protease inhibitors against hepatitis C virus. | 2014 Apr 28 | 24689657 |
Ligand bioactive conformation plays a critical role in the design of drugs that target the hepatitis C virus NS3 protease. | 2014 Mar 13 | 24144444 |
Cleavage of the T cell protein tyrosine phosphatase by the hepatitis C virus nonstructural 3/4A protease induces a Th1 to Th2 shift reversible by ribavirin therapy. | 2014 Feb 15 | 24442435 |
Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. | 2014 Feb | 23929719 |
Novel, sulfonamide linked inhibitors of the hepatitis C virus NS3 protease. | 2014 Feb 1 | 24405705 |
A 3D structural model and dynamics of hepatitis C virus NS3/4A protease (genotype 4a, strain ED43) suggest conformational instability of the catalytic triad: implications in catalysis and drug resistivity. | 2014 | 23768174 |
In vitro phenotypic characterization of hepatitis C virus NS3 protease variants observed in clinical studies of telaprevir. | 2013 Dec | 24100495 |
Azetidines and spiro azetidines as novel P2 units in hepatitis C virus NS3 protease inhibitors. | 2013 Dec 1 | 24135727 |