TitleDatePubMed ID
Evidence for substrate binding-induced zwitterion formation in the catalytic Cys-His dyad of the SARS-CoV main protease.2014 Sep 2325196915
Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding.2013 Nov 1524080461
Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: design, synthesis, biological evaluation, and docking studies.2013 Oct23994330
Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: structure-activity relationship study.2013 Jul23747811
Autoprocessing mechanism of severe acute respiratory syndrome coronavirus 3C-like protease (SARS-CoV 3CLpro) from its polyproteins.2013 May23452147
Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease.2013 May23633583
Structure-based design, synthesis, and evaluation of peptide-mimetic SARS 3CL protease inhibitors.2011 Dec 822014094
Peptide aldehyde inhibitors challenge the substrate specificity of the SARS-coronavirus main protease.2011 Nov21854807
Virtual screening identification of novel severe acute respiratory syndrome 3C-like protease inhibitors and in vitro confirmation.2011 May 1521470860
Increase of SARS-CoV 3CL peptidase activity due to macromolecular crowding effects in the milieu composition.2010 Dec21087086