Title | Date | PubMed ID |
Enhanced brain distribution of modified aspartoacylase. | 2014 Nov | 25066302 |
Aspartoacylase catalytic deficiency as the cause of Canavan disease: a structural perspective. | 2014 Aug 5 | 25003821 |
Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival. | 2014 Jul 28 | 25024137 |
Reexamination of aspartoacylase: is this human enzyme really a glycoprotein? | 2014 Apr 15 | 24632142 |
Aspartoacylase supports oxidative energy metabolism during myelination. | 2012 Sep | 22617649 |
A novel aspartoacylase (ASPA) gene mutation in Canavan disease. | 2012 Aug | 22468686 |
Modification of aspartoacylase for potential use in enzyme replacement therapy for the treatment of Canavan disease. | 2011 Feb | 21095151 |
Molecular dynamics and density functional theory studies of substrate binding and catalysis of human brain aspartoacylase. | 2010 Jun | 20227313 |
Lack of aspartoacylase activity disrupts survival and differentiation of neural progenitors and oligodendrocytes in a mouse model of Canavan disease. | 2009 Nov 15 | 19739253 |
Are astrocytes the missing link between lack of brain aspartoacylase activity and the spongiform leukodystrophy in Canavan disease? | 2009 Sep | 19319678 |