Title | Date | PubMed ID |
Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1. | 2018 Jun 6 | 29792696 |
Spectroscopic evidence for cofactor-substrate interaction in the radical-SAM enzyme TYW1. | 2017 Oct 10 | 28640310 |
4-Demethylwyosine synthase from Pyrococcus abyssi is a radical-S-adenosyl-L-methionine enzyme with an additional [4Fe-4S](+2) cluster that interacts with the pyruvate co-substrate. | 2012 Nov 30 | 23043105 |
Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine. | 2011 Dec 13 | 22026549 |
Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA. | 2007 Oct 5 | 17727881 |
Structure of an archaeal TYW1, the enzyme catalyzing the second step of wye-base biosynthesis. | 2007 Oct | 17881823 |
Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. | 2006 May 17 | 16642040 |