TitleDatePubMed ID
Glutamine Hydrolysis by Imidazole Glycerol Phosphate Synthase Displays Temperature Dependent Allosteric Activation.201829468164
Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activity.2017 Apr 2528396388
Combining ancestral sequence reconstruction with protein design to identify an interface hotspot in a key metabolic enzyme complex.2017 Feb27936490
Allosteric Communication Disrupted by a Small Molecule Binding to the Imidazole Glycerol Phosphate Synthase Protein-Protein Interface.2016 Nov 2927797506
The interaction of ammonia and xenon with the imidazole glycerol phosphate synthase from Thermotoga maritima as detected by NMR spectroscopy.2010 Sep20665694
Millisecond dynamics in the allosteric enzyme imidazole glycerol phosphate synthase (IGPS) from Thermotoga maritima.2009 Sep19565337
Structural elements in IGP synthase exclude water to optimize ammonia transfer.2005 Jul15849257
Substrate-induced changes in the ammonia channel for imidazole glycerol phosphate synthase.2003 Jun 1712795596
Toward understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerolphosphate synthase: crystal structures of a ternary complex and the free enzyme.2003 Jun 1712795595
Structure of imidazole glycerol phosphate synthase from Thermus thermophilus HB8: open-closed conformational change and ammonia tunneling.2002 Nov12417026