Title | Date | PubMed ID |
Steroidomimetic aminomethyl spiroacetals as novel inhibitors of the enzyme Δ8,7-sterol isomerase in cholesterol biosynthesis. | 2014 Feb | 24493593 |
Stereoselective synthesis of a new class of potent and selective inhibitors of human Δ8,7-sterol isomerase. | 2013 Apr 1 | 23433667 |
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Δ(8)-Δ(7) sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity. | 2011 Jan 3 | 21069657 |
Novel 4-(4-aryl)cyclohexyl-1-(2-pyridyl)piperazines as Delta(8)-Delta(7) sterol isomerase (emopamil binding protein) selective ligands with antiproliferative activity. | 2008 Dec 11 | 19053780 |
Identification of essential amino acid residues in a sterol 8,7-isomerase from Zea mays reveals functional homology and diversity with the isomerases of animal and fungal origin. | 2008 Sep 1 | 18459942 |
Molecular characterization of the microsomal tamoxifen binding site. | 2004 Aug 6 | 15175332 |
Purification, characterization and catalytic properties of human sterol 8-isomerase. | 2002 Nov 1 | 12133002 |
Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions. | 2001 Feb 1 | 11171067 |
Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization. | 1999 Jan 19 | 9894009 |
Isolation and characterization of an Arabidopsis thaliana C-8,7 sterol isomerase: functional and structural similarities to mammalian C-8,7 sterol isomerase/emopamil-binding protein. | 1998 Nov | 9862498 |