Title | Date | PubMed ID |
Optimal electrostatic interactions between substrate and protein are essential for radical chemistry in ornithine 4,5-aminomutase. | 2017 Aug | 28528213 |
Glutamate 338 is an electrostatic facilitator of C-Co bond breakage in a dynamic/electrostatic model of catalysis by ornithine aminomutase. | 2015 Apr | 25627283 |
A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes. | 2014 Dec 5 | 25213862 |
Quantum mechanics/molecular mechanics studies on the mechanism of action of cofactor pyridoxal 5'-phosphate in ornithine 4,5-aminomutase. | 2014 Sep 1 | 25048616 |
Isotope effects for deuterium transfer and mutagenesis of Tyr187 provide insight into controlled radical chemistry in adenosylcobalamin-dependent ornithine 4,5-aminomutase. | 2014 Aug 26 | 25100213 |
Large-scale domain motions and pyridoxal-5'-phosphate assisted radical catalysis in coenzyme B12-dependent aminomutases. | 2014 Feb 20 | 24562332 |
Mutagenesis of a conserved glutamate reveals the contribution of electrostatic energy to adenosylcobalamin co-C bond homolysis in ornithine 4,5-aminomutase and methylmalonyl-CoA mutase. | 2013 Feb 5 | 23311430 |
Role of histidine 225 in adenosylcobalamin-dependent ornithine 4,5-aminomutase. | 2012 Feb | 21899873 |
Large-scale domain conformational change is coupled to the activation of the Co-C bond in the B12-dependent enzyme ornithine 4,5-aminomutase: a computational study. | 2012 Feb 1 | 22239442 |
Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. | 2010 Apr 30 | 20106986 |