Title | Date | PubMed ID |
Insight into the cellular involvement of the two reverse gyrases from the hyperthermophilic archaeon Sulfolobus solfataricus. | 2014 Sep 9 | 25200003 |
A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation. | 2014 Jun 1 | 24775914 |
The reverse gyrase from Pyrobaculum calidifontis, a novel extremely thermophilic DNA topoisomerase endowed with DNA unwinding and annealing activities. | 2014 Feb 7 | 24347172 |
QSAR and docking studies on xanthone derivatives for anticancer activity targeting DNA topoisomerase IIα. | 2014 | 24516330 |
Substrate-mediated proton relay mechanism for the religation reaction in topoisomerase II. | 2014 | 24047515 |
Gossypol interferes with both type I and type II topoisomerase activities without generating strand breaks. | 2013 May | 23161103 |
Effect of short peptides containing lysine and epsilon-aminocaproic acid on fibrinolytic activity of plasmin and topoisomerase II action on supercoiled DNA. | 2013 May-Jun | 23757933 |
Topoisomerase II-mediated DNA cleavage and mutagenesis activated by nitric oxide underlie the inflammation-associated tumorigenesis. | 2013 Apr 1 | 22998676 |
A cysteine-reactive alkyl hydroquinone modifies topoisomerase IIα, enhances DNA breakage, and induces apoptosis in cancer cells. | 2012 Nov 19 | 23088786 |
Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity. | 2012 Nov | 23022727 |