Chloromycetny
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Basic Info
| Common Name | Chloromycetny(F01073) |
| 2D Structure | |
| FRCD ID | F01073 |
| CAS Number | 579-51-1 |
| PubChem CID | 298 |
| Formula | C11H12Cl2N2O5 |
| IUPAC Name | 2,2-dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide |
| InChI Key | WIIZWVCIJKGZOK-UHFFFAOYSA-N |
| InChI | InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18) |
| Canonical SMILES | C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] |
| Isomeric SMILES | C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] |
| Synonyms |
Tyfomycine
579-51-1
EN300-50870
Chloromycetin Hydrocortisone
Chloromyxin
Mycochlorin
Ocuphenicol
Chlorocin
Levocin
2,2-dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
|
| Classifies |
Veterinary Drug
|
| Update Date | Nov 13, 2018 16:49 |
Chemical Taxonomy
| Kingdom | Organic compounds |
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Nitrobenzenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Nitrobenzenes |
| Alternative Parents |
|
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Nitrobenzene - Nitroaromatic compound - Carboxamide group - C-nitro compound - Secondary alcohol - Secondary carboxylic acid amide - Organic nitro compound - Carboxylic acid derivative - Organic oxoazanium - Allyl-type 1,3-dipolar organic compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Primary alcohol - Organooxygen compound - Organonitrogen compound - Organochloride - Alkyl chloride - Organohalogen compound - Organopnictogen compound - Organic oxygen compound - Alcohol - Organic nitrogen compound - Aromatic alcohol - Organic zwitterion - Alkyl halide - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as nitrobenzenes. These are compounds containing a nitrobenzene moiety, which consists of a benzene ring with a carbon bearing a nitro group. |
Properties
| Property Name | Property Value |
|---|---|
| Molecular Weight | 323.126 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 5 |
| Complexity | 342 |
| Monoisotopic Mass | 322.012 |
| Exact Mass | 322.012 |
| XLogP | 1.1 |
| Formal Charge | 0 |
| Heavy Atom Count | 20 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 2 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Isotope Atom Count | 0 |
| Covalently-Bonded Unit Count | 1 |
References
| Title | Journal | Date | Pubmed ID |
|---|---|---|---|
| Combined effects of insecticide exposure and predation risk on freshwaterdetritivores. | Ecotoxicology | 2018 Jan 8 | 29313302 |
| Antibiotic effects on seed germination and root development of tomato (Solanumlycopersicum L.). | Ecotoxicol Environ Saf | 2018 Feb | 29035755 |
| Enantioselective analysis of chloramphenicol residues in honey samples by chiral LC-MS/MS and results of a honey survey. | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | 2017Jun | 28406359 |
| Chloramphenicol stereoisomers need to be distinguished: consequences observedfrom a proficiency test. | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | 2017Apr | 28093042 |
| A label-free and universal platform for antibiotics detection based on microchip electrophoresis using aptamer probes. | Talanta | 2017 May 15 | 28340759 |
| Design of elution strategy for simultaneous detection of chloramphenicol andgentamicin in complex samples using surface plasmon resonance. | Biosens Bioelectron | 2017 Jun 15 | 28231554 |
| Exploration of deep eutectic solvent-based molecularly imprinted polymers assolid-phase extraction sorbents for screening chloramphenicol in milk. | J Chromatogr Sci | 2017 Jul 1 | 28334778 |
| Photoresponsive colorimetric immunoassay based on chitosan modified AgI/TiO2heterojunction for highly sensitive chloramphenicol detection. | Biosens Bioelectron | 2017 Jan 15 | 27619522 |
| Novel single-stranded DNA binding protein-assisted fluorescence aptamer switchbased on FRET for homogeneous detection of antibiotics. | Biosens Bioelectron | 2017 Jan 15 | 27596250 |
| Interfacing DNA Oligonucleotides with Calcium Phosphate and Other MetalPhosphates. | Langmuir | 2017 Dec 27 | 29228772 |
| Determination of Aflatoxin M1 and Chloramphenicol in Milk Based on Background Fluorescence Quenching Immunochromatographic Assay. | Biomed Res Int | 2017 | 28367449 |
| Development of magnetic molecularly imprinted polymers with double templates for the rapid and selective determination of amphenicol antibiotics in water, blood, and egg samples. | J Chromatogr A | 2016 Nov 18 | 27816223 |
| Performance Assessment and Comparability of a Commercial Enzyme-LinkedImmunosorbent Assay Kit with Liquid Chromatography-Tandem Mass Spectrometry forChloramphenicol Residues in Crab and Shrimp. | J Food Prot | 2016 Jan | 26735037 |
| Separation, concentration and determination of trace chloramphenicol in shrimpfrom different waters by using polyoxyethylene lauryl ether-salt aqueoustwo-phase system coupled with high-performance liquid chromatography. | Food Chem | 2016 Feb 1 | 26304334 |
| A triple-amplification SPR electrochemiluminescence assay for chloramphenicolbased on polymer enzyme-linked nanotracers and exonuclease-assisted targetrecycling. | Biosens Bioelectron | 2016 Dec 15 | 27434234 |
| A highly selective electrochemical sensor for chloramphenicol based onthree-dimensional reduced graphene oxide architectures. | Talanta | 2016 Dec 1 | 27769449 |
| Selection and Identification of Chloramphenicol-Specific DNA Aptamers byMag-SELEX. | Appl Biochem Biotechnol | 2016 Dec | 27613616 |
| Engineered "hot" core-shell nanostructures for patterned detection ofchloramphenicol. | Biosens Bioelectron | 2016 Apr 15 | 26594888 |
| A sensitive electrochemical aptasensor for multiplex antibiotics detection based on high-capacity magnetic hollow porous nanotracers coupling exonuclease-assistedcascade target recycling. | Biosens Bioelectron | 2016 Apr 15 | 26594886 |
| Rapid surface enhanced Raman scattering detection method for chloramphenicolresidues. | Spectrochim Acta A Mol Biomol Spectrosc | 2015 Jun 5 | 25754387 |