FRCD

Trimethylamine is a uremic toxin. Uremic toxins can be subdivided into three major groups based upon their chemical and physical characteristics: 1) small, water-soluble, non-protein-bound compounds, such as urea; 2) small, lipid-soluble and/or protein-bound compounds, such as the phenols and 3) larger so-called middle-molecules, such as beta2-microglobulin. Chronic exposure of uremic toxins can lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular disease.
Trimethylamine, also known as NMe3, N(CH3)3, and TMA, is a colorless, hygroscopic, and flammable simple amine with a typical fishy odor in low concentrations and an ammonia like odor in higher concentrations. Trimethylamine has a boiling point of 2.9 degree centigrade and is a gas at room temperature. Trimethylamine usually comes in pressurized gas cylinders or as a 40% solution in water. Trimethylamine is a nitrogenous base and its positively charged cation is called trimethylammonium cation. A common salt of trimethylamine is trimethylammonium chloride, a hygroscopic colorless solid. Trimethylamine is a product of decomposition of plants and animals. It is the substance mainly responsible for the fishy odor often associated with fouling fish, bacterial vagina infections, and bad breath. It is also associated with taking large doses of choline. Trimethylaminuria is a genetic disorder in which the body is unable to metabolize trimethylamine from food sources. Patients develop a characteristic fish odour of their sweat, urine, and breath after the consumption of choline-rich foods. Trimethylaminuria is an autosomal recessive disorder involving a trimethylamine oxidase deficiency. Trimethylaminuria has also been observed in a certain breed of Rhode Island Red chicken that produces eggs with a fishy smell.

N,N-dimethylmethanamine

GETQZCLCWQTVFV-UHFFFAOYSA-N

InChI=1S/C3H9N/c1-4(2)3/h1-3H3

CN(C)C

CN(C)C

        
            trimethylamine
        
            N,N-dimethylmethanamine
        
            75-50-3
        
            Methanamine, N,N-dimethyl-
        
            Dimethylmethaneamine
        
            N-Trimethylamine
        
            Trimethylamine solution
        
            (CH3)3N
        
            TRIMETHYL AMINE
        
            Trimethylamin
        

                

                  
                    Predicted: Pesticide
                  

                
        

• Hydrocarbon derivatives
• Organopnictogen compounds