FRCD

3-Methoxytyrosine is one of the main biochemical markers for Aromatic L-amino acid decarboxylase (AADC, EC 4.1.1.28) deficiency, an inborn error of metabolism that affects serotonin and dopamine biosynthesis. Patients are usually detected in infancy due to developmental delay, hypotonia, and extrapyramidal movements. Diagnosis is based on an abnormal neurotransmitter metabolite profile in CSF and reduced AADC activity in plasma. 3-methoxytyrosine is elevated in CSF, plasma, and urine. (A3381, A3382, A3383).

2-amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid

PFDUUKDQEHURQC-UHFFFAOYSA-N

InChI=1S/C10H13NO4/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14/h2-3,5,7,12H,4,11H2,1H3,(H,13,14)

COC1=C(C=CC(=C1)CC(C(=O)O)N)O

COC1=C(C=CC(=C1)CC(C(=O)O)N)O

        
            DL-Tyrosine, 3-methoxy-
        
            3-Methoxytyrosine
        
            7636-26-2
        
            2-amino-3-(4-hydroxy-3-methoxyphenyl)propanoic acid
        
            3-METHOXY-DL-TYROSINE
        
            3-Methoxy-tyrosine
        
            L-3-Methoxytyrosine
        
            4214-13-5
        
            3-Methoxy-D,L-tyrosine
        
            PFDUUKDQEHURQC-UHFFFAOYSA-N
        

                

                  
                    Animal Toxin
                  

                
        

• Hydrocarbon derivatives
• Organic oxides
• Carbonyl compounds
• Organopnictogen compounds
• Methoxybenzenes
• 1-hydroxy-2-unsubstituted benzenoids
• Phenoxy compounds
• Methoxyphenols
• Alkyl aryl ethers
• Anisoles
• Monocarboxylic acids and derivatives
• Carboxylic acids
• Monoalkylamines
• Amino acids
• Aralkylamines
• Alpha amino acids
• Amphetamines and derivatives
• Phenylpropanoic acids
• Phenylalanine and derivatives