Amprolium
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Basic Info
| Common Name | Amprolium(F05855) |
| 2D Structure | |
| FRCD ID | F05855 |
| CAS Number | 121-25-5 |
| PubChem CID | 73341 |
| Formula | C14H19ClN4 |
| IUPAC Name | 5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propylpyrimidin-4-amine;chloride |
| InChI Key | LCTXBFGHZLGBNU-UHFFFAOYSA-M |
| InChI | InChI=1S/C14H19N4.ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);1H/q+1;/p-1 |
| Canonical SMILES | CCCC1=NC=C(C(=N1)N)C[N+]2=CC=CC=C2C.[Cl-] |
| Isomeric SMILES | CCCC1=NC=C(C(=N1)N)C[N+]2=CC=CC=C2C.[Cl-] |
| Synonyms |
amprolium
121-25-5
Amprolio
Amprovine
Amprol, Veterinary
Amprolium [INN:BAN]
Amprolium [INN-Latin]
Amprolio [INN-Spanish]
UNII-71M75T660B
EINECS 204-458-4
|
| Classifies |
Predicted: Pesticide
|
| Update Date | Nov 13, 2018 17:07 |
Chemical Taxonomy
| Kingdom | Organic compounds |
| Superclass | Organoheterocyclic compounds |
| Class | Pyridines and derivatives |
| Subclass | Methylpyridines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Methylpyridines |
| Alternative Parents | |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Methylpyridine - Imidolactam - Pyrimidine - Pyridinium - Hydropyrimidine - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic chloride salt - Organic salt - Organonitrogen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as methylpyridines. These are organic compounds containing a pyridine ring substituted at one or more positions by a methyl group. |
Properties
| Property Name | Property Value |
|---|---|
| Molecular Weight | 278.784 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Complexity | 246 |
| Monoisotopic Mass | 278.13 |
| Exact Mass | 278.13 |
| Formal Charge | 0 |
| Heavy Atom Count | 19 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Isotope Atom Count | 0 |
| Covalently-Bonded Unit Count | 2 |
MRLs
| Food | Product Code | Country | MRLs | Application Date | Notes |
|---|---|---|---|---|---|
| Muscle Of Pheasants | United States | 0.5ppm | |||
| Liver Of Pheasants | United States | 1ppm | |||
| Kidney Of Calves | United States | 0.5ppm | |||
| Liver Of Calves | United States | 0.5ppm | |||
| Muscle Tissue Of Calves | United States | 0.5ppm | |||
| Fat Of Calves | United States | 2. oppm | |||
| Whole Eggs Of Turkeys | United States | 4ppm | |||
| Whole Eggs Of Chickens | United States | 4ppm | |||
| Muscle Of Turkeys | United States | 0.5ppm | |||
| Muscle Of Chickens | United States | 0.5ppm | |||
| Kidney Of Turkeys | United States | 1ppm | |||
| Liver Of Chickens | United States | 1ppm | |||
| Other Poultry Animals,Edible Offal | Japan | 1ppm | |||
| Chicken,Edible Offal | Japan | 0.03ppm | |||
| Other Poultry Animals,Kidney | Japan | 1ppm | |||
| Chicken,Kidney | Japan | 0.03ppm | |||
| Other Poultry Animals,Liver | Japan | 1ppm | |||
| Chicken,Liver | Japan | 0.03ppm | |||
| Other Poultry Animals,Fat | Japan | 0.5ppm | |||
| Chicken,Fat | Japan | 0.03ppm |
References
| Title | Journal | Date | Pubmed ID |
|---|---|---|---|
| A multi-residue method for 17 anticoccidial drugs and ractopamine in animaltissues by liquid chromatography-tandem mass spectrometry and time-of-flight massspectrometry. | Drug Test Anal | 2016 May | 27443201 |
| The effect of composting on the persistence of four ionophores in dairy manureand poultry litter. | Waste Manag | 2016 Aug | 27189139 |
| Anticoccidial activity of herbal complex in broiler chickens challenged withEimeria tenella. | Parasitology | 2012 Feb | 22018334 |
| Assessment of antimicrobial usage and residues in commercial chicken eggs fromsmallholder poultry keepers in Morogoro municipality, Tanzania. | Zoonoses Public Health | 2010 Aug | 19486498 |
| Determination of amprolium in feed by a liquid chromatography-mass spectrometrymethod. | J Pharm Biomed Anal | 2008 Dec 15 | 18977627 |
| Efficacy of some anticoccidial drugs for treating coccidial enteritis of thecommon carp caused by Goussia carpelli (Apicomplexa: Eimeriidae). | Acta Vet Hung | 2007 Mar | 17385557 |
| Simplified high-performance liquid chromatographic determination of residual amprolium in edible chicken tissues. | J Chromatogr Sci | 2002 Jul | 12137209 |
| Simplified high-performance liquid chromatographic determination of residual amprolium in edible chicken tissues. | J Chromatogr Sci | 2002 Aug | 12201476 |
| Oral pharmacological treatments for parasitic diseases of rainbow troutOncorhynchus mykiss. II. Gyrodactylus sp. | Dis Aquat Organ | 1998 Jul 30 | 9745715 |
| Residual activity of anticoccidial drugs in chickens after withdrawal ofmedicated feeds. | Vet Parasitol | 1998 Jan 31 | 9561697 |
| Cerebral encephalomalacia in commercial turkeys. | Avian Dis | 1993 Jul-Sep | 8257395 |
| [Coccidiosis in lambs: observations in the preventive use of anamprolium-containing medicated feed]. | Tijdschr Diergeneeskd | 1989 Jun 1 | 2741152 |
| Determination of amprolium in egg yolk and muscle tissue (chicken) by HPLC withpost-column reaction and fluorometric detection, using on-line sample clean-upand pre-concentration steps. | Z Lebensm Unters Forsch | 1988 Jun | 3407321 |
| Anticoccidial drugs for preventive therapy in intensively reared pheasants. | Vet Rec | 1981 Dec 19 | 7336544 |
| The short-term toxicity of some feed additives to different freshwater organisms. | Bull Environ Contam Toxicol | 1976 Jun | 938765 |
| Anticoccidial effect of mananoligosacharide against experimentally inducedcoccidiosis in broiler. | None | None | 27068898 |
| Efficacy of selected oral chemotherapeutants against Ichthyophthirius multifiliis(Ciliophora: Ophyroglenidae) infecting rainbow trout Oncorhynchus mykiss. | None | None | 12887250 |