Kinesin-like protein KIF3C

NameKinesin-like protein KIF3C
Synonyms
Gene NameKIF3C
OrganismHuman
Amino acid sequence
>lcl|BSEQ0019734|Kinesin-like protein KIF3C
MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTF
DAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVI
PNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL
SSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG
KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL
GNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFAN
RAKNIKNKPQVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG
YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRS
LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE
LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA
EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWK
FQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPA
VFEMEFSHDQEQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPQRPPPSTTHASLA
SASLRPATVADHE
Number of residues793
Molecular Weight89425.56
Theoretical pINone
GO Classification
Functions
    ATP binding
ATPase activity
motor activity
microtubule motor activity
Processes
    antigen processing and presentation of exogenous peptide antigen via MHC class II
cytoskeleton-dependent intracellular transport
organelle organization
microtubule-based movement
organelle transport along microtubule
blood coagulation
Components
    primary cilium
microtubule
kinesin complex
ciliary tip
cytosol
General FunctionMotor activity
Specific FunctionMicrotubule-based anterograde translocator for membranous organelles.
Transmembrane Regions
GenBank Protein ID
UniProtKB IDO14782
UniProtKB Entry NameKIF3C_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0019735|Kinesin-like protein KIF3C (KIF3C)
ATGGCCAGTAAGACCAAGGCCAGCGAGGCCCTCAAGGTGGTGGCCCGGTGCCGCCCCCTC
AGCAGGAAGGAGGAGGCTGCTGGTCACGAGCAGATCCTGACCATGGACGTGAAACTGGGC
CAGGTGACCCTGCGGAACCCCCGCGCCGCCCCGGGGGAGCTGCCCAAGACCTTCACCTTT
GACGCCGTGTATGATGCCAGCTCCAAGCAGGCCGACCTGTATGACGAAACCGTGAGGCCC
CTGATAGACTCCGTGCTCCAGGGTTTCAATGGCACGGTGTTTGCCTATGGCCAGACGGGC
ACTGGCAAGACCTATACCATGCAGGGGACCTGGGTGGAGCCCGAGCTGCGCGGGGTCATC
CCGAATGCCTTTGAGCACATCTTCACCCACATCTCCCGCTCCCAGAACCAACAGTACCTG
GTCCGGGCCTCCTATTTGGAGATCTACCAGGAAGAGATTCGAGACCTGCTCTCCAAGGAG
CCGGGCAAGAGGCTAGAGCTGAAAGAGAACCCCGAGACTGGCGTCTACATCAAGGACCTC
TCCTCCTTCGTCACCAAGAATGTCAAGGAGATTGAGCATGTGATGAACCTGGGGAACCAG
ACCCGGGCTGTGGGCAGCACCCACATGAATGAGGTCAGCTCCCGCTCCCATGCCATCTTC
ATCATCACTGTGGAGTGCAGCGAACGTGGCTCTGATGGCCAGGACCACATCCGAGTGGGC
AAGCTCAACCTCGTGGACCTGGCTGGCAGCGAGAGGCAGAACAAGGCAGGCCCCAACACA
GCGGGAGGGGCAGCCACACCATCCTCGGGTGGCGGTGGTGGCGGTGGAGGCAGTGGTGGT
GGTGCTGGTGGAGAGAGGCCTAAGGAAGCCTCCAAAATCAACCTCTCATTATCTGCCCTG
GGCAACGTGATTGCTGCCCTGGCGGGCAACAGGAGCACCCACATTCCCTACCGGGACTCC
AAGCTGACCCGGCTGCTCCAGGACTCCCTGGGGGGGAATGCCAAGACCATCATGGTAGCC
ACACTGGGGCCAGCTTCTCACAGCTACGATGAGAGCCTCTCCACCTTGCGCTTTGCCAAC
CGAGCCAAGAACATCAAGAACAAGCCCCGGGTGAACGAGGACCCCAAGGACACACTGCTG
CGGGAATTCCAAGAGGAGATTGCCCGCCTGAAGGCCCAGCTGGAGAAGAGGGGGATGCTG
GGGAAGCGGCCCCGGAGGAAGAGCAGCCGCAGGAAGAAGGCCGTGTCCGCCCCGCCTGGG
TACCCTGAGGGCCCAGTGATTGAGGCCTGGGTGGCAGAAGAGGAGGATGACAACAACAAC
AACCACCGCCCGCCCCAGCCCATCCTGGAGTCAGCCTTGGAGAAGAACATGGAGAATTAC
CTGCAGGAACAGAAGGAGCGGCTGGAGGAGGAGAAGGCAGCCATCCAGGATGACCGCAGC
CTGGTGAGCGAGGAGAAGCAGAAGCTGCTGGAGGAGAAGGAGAAGATGCTGGAGGACCTG
CGGCGGGAACAGCAGGCCACAGAGCTGCTTGCGGCCAAGTACAAGGCCATGGAGAGCAAG
CTCCTCATCGGGGGCAGGAACATCATGGATCACACCAACGAACAGCAGAAGATGTTGGAA
CTGAAGAGGCAGGAGATTGCCGAGCAGAAACGTCGTGAGCGGGAGATGCAGCAGGAGATG
ATGCTCCGGGACGAGGAGACTATGGAGCTCCGGGGCACCTACACATCCCTGCAGCAGGAG
GTGGAGGTCAAAACCAAGAAACTCAAGAAGCTCTACGCCAAGCTGCAGGCGGTGAAGGCG
GAGATCCAGGACCAGCATGATGAGTATATCCGCGTGCGGCAGGACCTGGAGGAGGCGCAG
AACGAGCAGACCCGCGAACTCAAGCTCAAGTACCTAATCATCGAGAACTTCATCCCGCCG
GAGGAGAAGAACAAGATCATGAACCGGCTTTTCCTGGACTGTGAGGAGGAGCAGTGGAAG
TTCCAGCCACTGGTGCCAGCCGGCGTCAGTAGCAGCCAGATGAAGAAGCGGCCAACATCT
GCAGTGGGCTACAAGAGGCCTATCAGCCAGTATGCTCGGGTTGCCATGGCAATGGGGTCC
CACCCCAGGTACAGGGCTGAAAACATAATGTTTCTGGAGTTGGATGTGTCCCCTCCAGCT
GTCTTTGAGATGGAATTCTCTCACGACCAAGAACAAGACCCTCGTGCGCTACACATGGAG
AGGCTCATGCGATTGGACAGCTTTCTGGAAAGACCTTCCACGTCTAAAGTCCGAAAGTCC
AGATCCTGGTGCCAGAGTCCTCAGCGGCCTCCACCTTCCACCACACATGCCTCCCTGGCC
TCTGCTTCTCTGCGCCCTGCAACAGTGGCGGACCATGAGTGA
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC IDHGNC:6321
Chromosome Location2
LocusNone
References
  1. Sardella M, Navone F, Rocchi M, Rubartelli A, Viggiano L, Vignali G, Consalez GG, Sitia R, Cabibbo A: KIF3C, a novel member of the kinesin superfamily: sequence, expression, and mapping to human chromosome 2 at 2p23. Genomics. 1998 Feb 1;47(3):405-8.[9480755 ]
  2. Telford EA, Wightman P, Leek J, Markham AF, Lench NJ, Bonthron DT: cDNA cloning, genomic organization, and chromosomal localization of a novel human gene that encodes a kinesin-related protein highly similar to mouse Kif3C. Biochem Biophys Res Commun. 1998 Jan 14;242(2):407-12.[9446808 ]
  3. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7.[15489334 ]
  4. Hillier LW, Graves TA, Fulton RS, Fulton LA, Pepin KH, Minx P, Wagner-McPherson C, Layman D, Wylie K, Sekhon M, Becker MC, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Kremitzki C, Oddy L, Du H, Sun H, Bradshaw-Cordum H, Ali J, Carter J, Cordes M, Harris A, Isak A, van Brunt A, Nguyen C, Du F, Courtney L, Kalicki J, Ozersky P, Abbott S, Armstrong J, Belter EA, Caruso L, Cedroni M, Cotton M, Davidson T, Desai A, Elliott G, Erb T, Fronick C, Gaige T, Haakenson W, Haglund K, Holmes A, Harkins R, Kim K, Kruchowski SS, Strong CM, Grewal N, Goyea E, Hou S, Levy A, Martinka S, Mead K, McLellan MD, Meyer R, Randall-Maher J, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Shah N, Swearengen-Shahid S, Snider J, Strong JT, Thompson J, Yoakum M, Leonard S, Pearman C, Trani L, Radionenko M, Waligorski JE, Wang C, Rock SM, Tin-Wollam AM, Maupin R, Latreille P, Wendl MC, Yang SP, Pohl C, Wallis JW, Spieth J, Bieri TA, Berkowicz N, Nelson JO, Osborne J, Ding L, Meyer R, Sabo A, Shotland Y, Sinha P, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Jones TA, She X, Ciccarelli FD, Izaurralde E, Taylor J, Schmutz J, Myers RM, Cox DR, Huang X, McPherson JD, Mardis ER, Clifton SW, Warren WC, Chinwalla AT, Eddy SR, Marra MA, Ovcharenko I, Furey TS, Miller W, Eichler EE, Bork P, Suyama M, Torrents D, Waterston RH, Wilson RK: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature. 2005 Apr 7;434(7034):724-31.[15815621 ]

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