Kinesin-like protein KIF3B


NameKinesin-like protein KIF3B
SynonymsHH0048 KIAA0359 Microtubule plus end-directed kinesin motor 3B
Gene NameKIF3B
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009508|Kinesin-like protein KIF3B
MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFD
AVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIP
NSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLS
SFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGK
LNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRL
LQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQE
EIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEK
LEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKN
IVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKK
LKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIM
NRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENI
VLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSG
RKSGSSSSSSGTPASQLYPQSRGLVPK
Number of residues747
Molecular Weight85124.58
Theoretical pINone
GO Classification
Functions
    microtubule motor activity
    ATP-dependent microtubule motor activity, plus-end-directed
    ATP binding
    Rho GTPase binding
Processes
    mitotic centrosome separation
    blood coagulation
    plus-end-directed vesicle transport along microtubule
    anterograde axon cargo transport
    membrane organization
    antigen processing and presentation of exogenous peptide antigen via MHC class II
    mitotic spindle assembly
    organelle organization
    mitotic spindle organization
    determination of left/right symmetry
    microtubule-based movement
    positive regulation of cytokinesis
Components
    midbody
    kinesin II complex
    intraciliary transport particle
    cytosol
    extracellular exosome
    spindle
    membrane
    primary cilium
    plus-end kinesin complex
    microtubule cytoskeleton
    ciliary tip
    microtubule
    centrosome
General FunctionRho gtpase binding
Specific FunctionInvolved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity).
Transmembrane Regions
GenBank Protein ID
UniProtKB IDO15066
UniProtKB Entry NameKIF3B_HUMAN
Cellular LocationCytoplasm
Gene sequence
>lcl|BSEQ0021705|Kinesin-like protein KIF3B (KIF3B)
ATGTCAAAGTTGAAAAGCTCAGAGTCAGTCAGGGTGGTGGTTCGCTGTCGGCCCATGAAT
GGCAAGGAAAAGGCTGCTTCGTATGACAAAGTGGTGGATGTGGATGTTAAGCTGGGGCAG
GTGTCTGTGAAGAACCCCAAAGGGACGGCCCATGAAATGCCCAAGACCTTCACCTTTGAT
GCCGTCTATGACTGGAATGCCAAGCAGTTTGAACTGTACGATGAGACGTTCCGACCACTT
GTTGACTCTGTCCTGCAAGGTTTCAATGGAACCATTTTTGCCTATGGACAAACTGGGACA
GGAAAAACCTACACCATGGAAGGAATCCGTGGTGACCCTGAAAAAAGAGGAGTCATTCCT
AACTCATTTGACCATATCTTCACCCACATCTCTCGATCCCAGAATCAACAATACCTGGTC
AGGGCTTCTTACTTAGAGATCTACCAGGAGGAGATCCGAGATTTGCTCTCAAAGGATCAG
ACCAAAAGGCTTGAGCTCAAAGAGAGGCCTGACACAGGAGTGTATGTGAAAGACCTGTCT
TCCTTTGTCACCAAGAGTGTGAAGGAGATAGAGCATGTGATGAATGTGGGGAACCAGAAC
CGTTCTGTCGGTGCTACCAACATGAACGAGCACAGCTCGCGTTCTCATGCAATTTTCGTT
ATCACTATTGAGTGCAGCGAGGTGGGCCTCGATGGTGAAAACCACATCCGTGTAGGAAAA
TTGAACCTTGTAGATCTTGCTGGCAGCGAACGGCAAGCCAAGACCGGCGCACAAGGGGAG
AGATTAAAAGAAGCTACCAAGATCAACCTCTCCCTTTCCGCTTTGGGTAATGTCATCTCT
GCTCTAGTGGACGGCAAAAGCACTCACATTCCATATCGGGACTCAAAGCTTACCAGGCTC
CTCCAAGATTCCCTTGGTGGCAATGCCAAGACTGTGATGGTGGCCAACGTGGGGCCTGCC
TCTTACAACGTAGAAGAGACTCTGACCACTCTGCGATATGCCAACCGTGCCAAAAACATT
AAGAACAAACCAAGGGTCAATGAGGACCCCAAGGATGCCCTCCTTCGAGAATTCCAGGAA
GAGATTGCTCGGCTCAAGGCCCAGCTGGAAAAACGGTCCATTGGTAGGAGGAAGAGGCGA
GAGAAGCGGAGGGAAGGTGGTGGCAGTGGTGGGGGTGGGGAAGAGGAGGAGGAGGAGGGA
GAAGAGGGTGAGGAGGAAGGGGATGATAAGGATGATTACTGGCGGGAACAGCAAGAAAAA
CTGGAGATTGAGAAGCGGGCCATTGTAGAGGATCACAGCTTGGTTGCAGAGGAGAAGATG
AGGCTGCTGAAGGAGAAAGAGAAAAAGATGGAGGACCTGCGGCGGGAGAAGGATGCTGCC
GAGATGCTGGGCGCCAAGATCAAGGCCATGGAGAGTAAGTTGCTTGTTGGAGGAAAAAAT
ATAGTAGATCATACGAATGAACAGCAGAAAATCCTGGAGCAGAAACGACAGGAAATTGCA
GAGCAGAAACGTCGAGAAAGAGAAATCCAGCAACAGATGGAAAGTCGAGATGAGGAGACC
TTGGAACTTAAAGAGACATACAGCTCATTGCAGCAAGAGGTGGACATCAAGACCAAAAAA
CTCAAAAAGCTCTTCTCCAAGCTTCAGGCAGTGAAGGCTGAGATCCATGACCTCCAAGAA
GAACACATCAAGGAGCGCCAAGAGCTAGAGCAGACTCAGAATGAGCTCACCAGGGAGCTG
AAACTCAAGCATCTTATTATAGAAAACTTTATCCCTCTGGAAGAAAAAAGTAAAATTATG
AATAGAGCCTTCTTTGATGAAGAGGAAGATCATTGGAAACTACATCCTATAACCAGACTG
GAGAACCAGCAGATGATGAAGCGGCCAGTCTCAGCCGTGGGATATAAGAGACCATTGAGC
CAGCACGCAAGAATGTCCATGATGATTCGTCCAGAGGCCCGATATAGGGCAGAAAACATT
GTGCTGTTAGAGCTGGACATGCCCAGCCGGACCACCAGAGACTATGAGGGTCCAGCCATT
GCCCCCAAGGTCCAGGCTGCATTGGATGCGGCTCTGCAGGATGAAGATGAGATACAGGTG
GATGCATCATCATTTGAAAGCACTGCAAATAAGAAATCCAAGGCCAGGCCTAAAAGTGGA
AGGAAGTCGGGATCCTCCTCCTCTTCCTCAGGAACCCCTGCATCTCAGCTTTATCCACAG
TCTCGGGGGCTGGTTCCAAAGTAA
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC IDHGNC:6320
Chromosome Location20
LocusNone
References
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