Interferon beta
Name | Interferon beta |
---|---|
Synonyms | Fibroblast interferon IFB IFN-beta IFNB |
Gene Name | IFNB1 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0010650|Interferon beta MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFD IPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLK TVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINR LTGYLRN |
Number of residues | 187 |
Molecular Weight | 22293.68 |
Theoretical pI | 8.91 |
GO Classification |
Functions
type I interferon receptor binding cytokine activity chloramphenicol O-acetyltransferase activity Processes
cell surface receptor signaling pathway B cell differentiation negative regulation of viral genome replication defense response to bacterium natural killer cell activation positive regulation of innate immune response B cell proliferation response to exogenous dsRNA blood coagulation positive regulation of peptidyl-serine phosphorylation of STAT protein cytokine-mediated signaling pathway regulation of MHC class I biosynthetic process cellular response to dexamethasone stimulus B cell activation involved in immune response T cell activation involved in immune response positive regulation of apoptotic signaling pathway cellular response to exogenous dsRNA regulation of type I interferon-mediated signaling pathway cellular response to virus humoral immune response response to virus defense response to virus type I interferon signaling pathway natural killer cell activation involved in immune response innate immune response adaptive immune response negative regulation of T cell differentiation positive regulation of transcription from RNA polymerase II promoter cellular response to interferon-beta negative regulation of T-helper 2 cell cytokine production Components
extracellular region extracellular space |
General Function | Type i interferon receptor binding |
Specific Function | Has antiviral, antibacterial and anticancer activities. |
Transmembrane Regions | |
GenBank Protein ID | 32638 |
UniProtKB ID | P01574 |
UniProtKB Entry Name | IFNB_HUMAN |
Cellular Location | Secreted |
Gene sequence | >lcl|BSEQ0010651|Interferon beta (IFNB1) ATGACCAACAAGTGTCTCCTCCAAATTGCTCTCCTGTTGTGCTTCTCCACTACAGCTCTT TCCATGAGCTACAACTTGCTTGGATTCCTACAAAGAAGCAGCAATTTTCAGTGTCAGAAG CTCCTGTGGCAATTGAATGGGAGGCTTGAATACTGCCTCAAGGACAGGATGAACTTTGAC ATCCCTGAGGAGATTAAGCAGCTGCAGCAGTTCCAGAAGGAGGACGCCGCATTGACCATC TATGAGATGCTCCAGAACATCTTTGCTATTTTCAGACAAGATTCATCTAGCACTGGCTGG AATGAGACTATTGTTGAGAACCTCCTGGCTAATGTCTATCATCAGATAAACCATCTGAAG ACAGTCCTGGAAGAAAAACTGGAGAAAGAAGATTTCACCAGGGGAAAACTCATGAGCAGT CTGCACCTGAAAAGATATTATGGGAGGATTCTGCATTACCTGAAGGCCAAGGAGTACAGT CACTGTGCCTGGACCATAGTCAGAGTGGAAATCCTAAGGAACTTTTACTTCATTAACAGA CTTACAGGTTACCTCCGAAACTGA |
GenBank Gene ID | V00534 |
GeneCard ID | None |
GenAtlas ID | IFNB1 |
HGNC ID | HGNC:5434 |
Chromosome Location | 9 |
Locus | 9p21 |
References |
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Related FRC
FRCD ID | Name | Exact Mass | Structure |
---|---|---|---|
D-Glucose |
180.156 |