Ig alpha-1 chain C region
Name | Ig alpha-1 chain C region |
---|---|
Synonyms | |
Gene Name | IGHA1 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0008861|Ig alpha-1 chain C region ASPTSPKVFPLSLCSTQPDGNVVIACLVQGFFPQEPLSVTWSESGQGVTARNFPPSQDAS GDLYTTSSQLTLPATQCLAGKSVTCHVKHYTNPSQDVTVPCPVPSTPPTPSPSTPPTPSP SCCHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGVTFTWTPSSGKSAVQGPPERDLC GCYSVSSVLPGCAEPWNHGKTFTCTAAYPESKTPLTATLSKSGNTFRPEVHLLPPPSEEL ALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTFAVTSILRV AAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGKPTHVNVSVVMAEVDGTCY |
Number of residues | 353 |
Molecular Weight | 37654.29 |
Theoretical pI | None |
GO Classification |
Functions
antigen binding Processes
positive regulation of B cell activation Fc-epsilon receptor signaling pathway glomerular filtration receptor-mediated endocytosis phagocytosis, engulfment immune response retina homeostasis positive regulation of respiratory burst B cell receptor signaling pathway protein-chromophore linkage antibacterial humoral response complement activation, classical pathway Fc-gamma receptor signaling pathway involved in phagocytosis innate immune response phagocytosis, recognition Components
external side of plasma membrane monomeric IgA immunoglobulin complex blood microparticle secretory dimeric IgA immunoglobulin complex extracellular region secretory IgA immunoglobulin complex extracellular space extracellular exosome |
General Function | Antigen binding |
Specific Function | Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. |
Transmembrane Regions | |
GenBank Protein ID | |
UniProtKB ID | P01876 |
UniProtKB Entry Name | IGHA1_HUMAN |
Cellular Location | None |
Gene sequence | None |
GenBank Gene ID | |
GeneCard ID | None |
GenAtlas ID | |
HGNC ID | HGNC:5478 |
Chromosome Location | None |
Locus | None |
References |
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Related FRC
FRCD ID | Name | Exact Mass | Structure |
---|---|---|---|
Cobaltocene |
189.123 |
||
Adenosylcobalamin |
1579.608 |
||
Methylcobalamin |
1344.405 |
||
Hydroxocobalamin |
1346.377 |
||
Salcomine |
327.249 |
||
Cyanocobalamin |
1356.396 |