Ig alpha-2 chain C region
Name | Ig alpha-2 chain C region |
---|---|
Synonyms | |
Gene Name | IGHA2 |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0009530|Ig alpha-2 chain C region ASPTSPKVFPLSLDSTPQDGNVVVACLVQGFFPQEPLSVTWSESGQNVTARNFPPSQDAS GDLYTTSSQLTLPATQCPDGKSVTCHVKHYTNPSQDVTVPCPVPPPPPCCHPRLSLHRPA LEDLLLGSEANLTCTLTGLRDASGATFTWTPSSGKSAVQGPPERDLCGCYSVSSVLPGCA QPWNHGETFTCTAAHPELKTPLTANITKSGNTFRPEVHLLPPPSEELALNELVTLTCLAR GFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTFAVTSILRVAAEDWKKGDTFSC MVGHEALPLAFTQKTIDRMAGKPTHVNVSVVMAEVDGTCY |
Number of residues | 340 |
Molecular Weight | 36526.005 |
Theoretical pI | None |
GO Classification |
Functions
antigen binding Processes
receptor-mediated endocytosis phagocytosis, engulfment retina homeostasis positive regulation of respiratory burst immune response B cell receptor signaling pathway antibacterial humoral response complement activation, classical pathway Fc-gamma receptor signaling pathway involved in phagocytosis innate immune response phagocytosis, recognition positive regulation of B cell activation Fc-epsilon receptor signaling pathway glomerular filtration Components
monomeric IgA immunoglobulin complex blood microparticle secretory dimeric IgA immunoglobulin complex secretory IgA immunoglobulin complex extracellular region extracellular space extracellular exosome external side of plasma membrane |
General Function | Antigen binding |
Specific Function | Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. |
Transmembrane Regions | |
GenBank Protein ID | |
UniProtKB ID | P01877 |
UniProtKB Entry Name | IGHA2_HUMAN |
Cellular Location | None |
Gene sequence | None |
GenBank Gene ID | |
GeneCard ID | None |
GenAtlas ID | |
HGNC ID | HGNC:5479 |
Chromosome Location | None |
Locus | None |
References |
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Related FRC
FRCD ID | Name | Exact Mass | Structure |
---|---|---|---|
Cobaltocene |
189.123 |
||
Adenosylcobalamin |
1579.608 |
||
Methylcobalamin |
1344.405 |
||
Hydroxocobalamin |
1346.377 |
||
Salcomine |
327.249 |
||
Cyanocobalamin |
1356.396 |