Protamine-2


NameProtamine-2
SynonymsSperm histone P2 Sperm protamine P2
Gene NamePRM2
OrganismHuman
Amino acid sequence
>lcl|BSEQ0008800|Protamine-2
MVRYRVRSLSERSHEVYRQQLHGQEQGHHGQEEQGLSPEHVEVYERTHGQSHYRRRHCSR
RRLHRIHRRQHRSCRRRKRRSCRHRRRHRRGCRTRKRTCRRH
Number of residues102
Molecular Weight13050.695
Theoretical pINone
GO Classification
Functions
    DNA binding
Processes
    chromosome condensation
    DNA packaging
    cell differentiation
    multicellular organismal development
    spermatogenesis
Components
    nucleosome
    nucleus
    nucleoplasm
General FunctionDna binding
Specific FunctionProtamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
Transmembrane Regions
GenBank Protein ID
UniProtKB IDP04554
UniProtKB Entry NamePRM2_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0020823|Protamine-2 (PRM2)
ATGGTCCGATACCGCGTGAGGAGCCTGAGCGAACGCTCGCACGAGGTGTACAGGCAGCAG
TTGCATGGGCAAGAGCAAGGACACCACGGCCAAGAGGAGCAAGGGCTGAGCCCGGAGCAC
GTCGAGGTCTACGAGAGGACCCATGGCCAGTCTCACTATAGGCGCAGACACTGCTCTCGA
AGGAGGCTGCACCGGATCCACAGGCGGCAGCATCGCTCCTGCAGAAGGCGCAAAAGACGC
TCCTGCAGGCACCGGAGGAGGCATCGCAGAGAGTCCCTAGGTGACCCCCTCAACCAGAAC
TTTCTTTCCCAAAAGGCTGCAGAACCAGGAAGAGAACATGCAGAAGGCACTAAGCTTCCT
GGGCCCCTCACCCCCAGCTGGAAATTAAGAAAAAGTCGCCCGAAACACCAAGTGAGGCCA
TAG
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC IDHGNC:9448
Chromosome Location16
LocusNone
References
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