Cytochrome c oxidase subunit 4 isoform 1, mitochondrial


NameCytochrome c oxidase subunit 4 isoform 1, mitochondrial
SynonymsCOX IV-1 COX4 Cytochrome c oxidase polypeptide IV Cytochrome c oxidase subunit IV isoform 1
Gene NameCOX4I1
OrganismHuman
Amino acid sequence
>lcl|BSEQ0017288|Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
MLATRVFSLVGKRAISTSVCVRAHESVVKSEDFSLPAYMDRRDHPLPEVAHVKHLSASQK
ALKEKEKASWSSLSMDEKVELYRIKFKESFAEMNRGSNEWKTVVGGAMFFIGFTALVIMW
QKHYVYGPLPQSFDKEWVAKQTKRMLDMKVNPIQGLASKWDYEKNEWKK
Number of residues169
Molecular Weight19576.6
Theoretical pI10.12
GO Classification
Functions
    cytochrome-c oxidase activity
Processes
    hydrogen ion transmembrane transport
    mitochondrial electron transport, cytochrome c to oxygen
    aerobic respiration
    gene expression
    small molecule metabolic process
    transcription initiation from RNA polymerase II promoter
    generation of precursor metabolites and energy
    cellular metabolic process
    respiratory electron transport chain
    response to nutrient
Components
    mitochondrial respiratory chain complex IV
    mitochondrial inner membrane
    extracellular exosome
    mitochondrion
    membrane
    nucleus
General FunctionCytochrome-c oxidase activity
Specific FunctionThis protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Transmembrane Regions
GenBank Protein ID180933
UniProtKB IDP13073
UniProtKB Entry NameCOX41_HUMAN
Cellular LocationMitochondrion inner membrane
Gene sequence
>lcl|BSEQ0017289|Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)
ATGTTGGCTACCAGGGTATTTAGCCTAGTTGGCAAGCGAGCAATTTCCACCTCTGTGTGT
GTACGAGCTCATGAAAGTGTTGTGAAGAGCGAAGACTTTTCGCTCCCAGCTTATATGGAT
CGGCGTGACCACCCCTTGCCGGAGGTGGCCCATGTCAAGCACCTGTCTGCCAGCCAGAAG
GCATTGAAGGAGAAGGAGAAGGCCTCCTGGAGCAGCCTCTCCATGGATGAGAAAGTCGAG
TTGTATCGCATTAAGTTCAAGGAGAGCTTTGCTGAGATGAACAGGGGCTCGAACGAGTGG
AAGACGGTTGTGGGCGGTGCCATGTTCTTCATCGGTTTCACCGCGCTCGTTATCATGTGG
CAGAAGCACTATGTGTACGGCCCCCTCCCGCAAAGCTTTGACAAAGAGTGGGTGGCCAAG
CAGACCAAGAGGATGCTGGACATGAAGGTGAACCCCATCCAGGGCTTAGCCTCCAAGTGG
GACTACGAAAAGAACGAGTGGAAGAAGTGA
GenBank Gene IDM21575
GeneCard IDNone
GenAtlas ID
HGNC IDHGNC:2265
Chromosome Location16
Locus16q22-qter
References
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