Histone H2A type 1-D


NameHistone H2A type 1-D
SynonymsH2AFG Histone H2A.3 Histone H2A/g
Gene NameHIST1H2AD
OrganismHuman
Amino acid sequence
>lcl|BSEQ0017626|Histone H2A type 1-D
MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKK
TESHHKAKGK
Number of residues130
Molecular Weight14107.375
Theoretical pINone
GO Classification
Functions
    DNA binding
Processes
    chromatin silencing
    chromatin organization
Components
    nucleus
    extracellular exosome
    nuclear chromatin
    nucleosome
General FunctionDna binding
Specific FunctionCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Transmembrane Regions
GenBank Protein ID
UniProtKB IDP20671
UniProtKB Entry NameH2A1D_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0017627|Histone H2A type 1-D (HIST1H2AD)
ATGTCCGGACGCGGCAAGCAAGGCGGAAAGGCCCGAGCTAAGGCTAAGACCCGCTCTTCG
CGGGCCGGACTCCAGTTCCCTGTGGGCCGCGTACACCGCTTGCTCCGCAAGGGCAACTAC
TCCGAGCGAGTCGGGGCCGGCGCGCCAGTGTATCTGGCGGCGGTGTTGGAGTACCTGACC
GCCGAGATCCTGGAGCTGGCGGGCAACGCCGCCCGCGACAACAAGAAGACCCGCATCATC
CCCCGACACCTGCAGCTGGCCATCCGCAACGACGAGGAGCTAAACAAGTTGCTGGGTAAA
GTCACAATTGCTCAGGGCGGTGTTCTGCCCAACATCCAGGCTGTACTGCTCCCCAAGAAG
ACTGAGAGTCACCACAAGGCCAAGGGCAAGTAA
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC IDHGNC:4729
Chromosome Location6
LocusNone
References
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