Histone H2B type 1-B
Name | Histone H2B type 1-B |
---|---|
Synonyms | H2B/f H2BFF Histone H2B.1 Histone H2B.f |
Gene Name | HIST1H2BB |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0020836|Histone H2B type 1-B MPEPSKSAPAPKKGSKKAITKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAM GIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVT KYTSSK |
Number of residues | 126 |
Molecular Weight | 13950.075 |
Theoretical pI | None |
GO Classification |
Functions
DNA binding Processes
chromatin organization nucleosome assembly Components
cytoplasm nucleus nucleoplasm nuclear chromosome, telomeric region nucleosome |
General Function | Dna binding |
Specific Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Transmembrane Regions | |
GenBank Protein ID | |
UniProtKB ID | P33778 |
UniProtKB Entry Name | H2B1B_HUMAN |
Cellular Location | Nucleus |
Gene sequence | >lcl|BSEQ0020837|Histone H2B type 1-B (HIST1H2BB) ATGCCTGAACCCTCTAAGTCTGCTCCAGCCCCTAAAAAGGGTTCTAAGAAGGCTATCACT AAGGCGCAGAAGAAGGATGGTAAGAAGCGTAAGCGCAGCCGCAAGGAGAGCTATTCTATC TATGTGTACAAGGTTCTGAAGCAGGTCCACCCCGACACCGGCATCTCATCCAAGGCCATG GGGATCATGAATTCCTTCGTCAACGACATCTTCGAGCGCATCGCGGGCGAGGCTTCTCGC CTGGCTCACTACAATAAGCGCTCGACCATCACCTCCAGGGAGATTCAGACGGCTGTGCGC CTGCTGCTGCCTGGGGAGCTGGCTAAGCATGCTGTGTCCGAGGGCACTAAGGCAGTTACC AAGTACACTAGCTCTAAATAA |
GenBank Gene ID | |
GeneCard ID | None |
GenAtlas ID | |
HGNC ID | HGNC:4751 |
Chromosome Location | 6 |
Locus | None |
References |
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Related FRC
FRCD ID | Name | Exact Mass | Structure |
---|---|---|---|
Nickel chloride |
129.593 |
||
Benzene |
78.114 |
||
Nickel |
58.693 |
||
Nickelocene |
188.883 |