Histone H2B type 1-B
| Name | Histone H2B type 1-B |
|---|---|
| Synonyms | H2B/f H2BFF Histone H2B.1 Histone H2B.f |
| Gene Name | HIST1H2BB |
| Organism | Human |
| Amino acid sequence | >lcl|BSEQ0020836|Histone H2B type 1-B MPEPSKSAPAPKKGSKKAITKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAM GIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVT KYTSSK |
| Number of residues | 126 |
| Molecular Weight | 13950.075 |
| Theoretical pI | None |
| GO Classification |
Functions
DNA binding Processes
chromatin organization nucleosome assembly Components
cytoplasm nucleus nucleoplasm nuclear chromosome, telomeric region nucleosome |
| General Function | Dna binding |
| Specific Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Transmembrane Regions | |
| GenBank Protein ID | |
| UniProtKB ID | P33778 |
| UniProtKB Entry Name | H2B1B_HUMAN |
| Cellular Location | Nucleus |
| Gene sequence | >lcl|BSEQ0020837|Histone H2B type 1-B (HIST1H2BB) ATGCCTGAACCCTCTAAGTCTGCTCCAGCCCCTAAAAAGGGTTCTAAGAAGGCTATCACT AAGGCGCAGAAGAAGGATGGTAAGAAGCGTAAGCGCAGCCGCAAGGAGAGCTATTCTATC TATGTGTACAAGGTTCTGAAGCAGGTCCACCCCGACACCGGCATCTCATCCAAGGCCATG GGGATCATGAATTCCTTCGTCAACGACATCTTCGAGCGCATCGCGGGCGAGGCTTCTCGC CTGGCTCACTACAATAAGCGCTCGACCATCACCTCCAGGGAGATTCAGACGGCTGTGCGC CTGCTGCTGCCTGGGGAGCTGGCTAAGCATGCTGTGTCCGAGGGCACTAAGGCAGTTACC AAGTACACTAGCTCTAAATAA |
| GenBank Gene ID | |
| GeneCard ID | None |
| GenAtlas ID | |
| HGNC ID | HGNC:4751 |
| Chromosome Location | 6 |
| Locus | None |
| References |
|
Related FRC
| FRCD ID | Name | Exact Mass | Structure |
|---|---|---|---|
Nickelocene |
188.883 |
||
Nickel chloride |
129.593 |
||
Benzene |
78.114 |
||
Nickel |
58.693 |