DNA-directed RNA polymerase II subunit RPB9
Name | DNA-directed RNA polymerase II subunit RPB9 |
---|---|
Synonyms | DNA-directed RNA polymerase II subunit I RNA polymerase II 14.5 kDa subunit RNA polymerase II subunit B9 RPB14.5 |
Gene Name | POLR2I |
Organism | Human |
Amino acid sequence | >lcl|BSEQ0019709|DNA-directed RNA polymerase II subunit RPB9 MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITH EVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCG HRWTE |
Number of residues | 125 |
Molecular Weight | 14523.1 |
Theoretical pI | None |
GO Classification |
Functions
zinc ion binding DNA binding DNA-directed RNA polymerase activity Processes
nucleotide-excision repair gene silencing by RNA transcription from RNA polymerase II promoter mRNA splicing, via spliceosome piRNA metabolic process gene expression positive regulation of viral transcription transcription initiation from RNA polymerase II promoter RNA splicing transcription elongation from RNA polymerase II promoter maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter somatic stem cell population maintenance transcription-coupled nucleotide-excision repair DNA repair viral process 7-methylguanosine mRNA capping Components
DNA-directed RNA polymerase II, core complex nucleolus nucleoplasm nucleus |
General Function | Zinc ion binding |
Specific Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity). |
Transmembrane Regions | |
GenBank Protein ID | |
UniProtKB ID | P36954 |
UniProtKB Entry Name | RPB9_HUMAN |
Cellular Location | Nucleus |
Gene sequence | >lcl|BSEQ0019710|DNA-directed RNA polymerase II subunit RPB9 (POLR2I) ATGGAGCCCGACGGGACTTACGAGCCGGGCTTCGTGGGTATTCGCTTCTGCCAGGAATGT AACAACATGCTGTACCCCAAGGAAGACAAGGAGAACCGCATTCTGCTCTACGCGTGCCGG AACTGTGATTACCAGCAGGAGGCCGACAACAGCTGCATCTATGTCAACAAGATCACGCAC GAAGTGGACGAACTGACCCAGATTATCGCCGACGTGTCCCAGGACCCCACGTTGCCGCGG ACCGAGGACCACCCGTGCCAAAAGTGCGGCCACAAGGAGGCTGTGTTCTTCCAGTCACAC AGTGCGCGGGCCGAGGACGCCATGCGCCTTTACTACGTGTGCACAGCCCCACACTGCGGC CACCGCTGGACCGAGTGA |
GenBank Gene ID | |
GeneCard ID | None |
GenAtlas ID | |
HGNC ID | HGNC:9196 |
Chromosome Location | 19 |
Locus | None |
References |
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Related FRC
FRCD ID | Name | Exact Mass | Structure |
---|---|---|---|
Amanullin |
886.979 |
||
Amaninamide |
902.978 |
||
Amanin |
903.962 |
||
Proamanullin |
870.98 |
||
Patulin |
154.121 |
||
Luteoskyrin |
574.494 |