Acidic phospholipase A2 3

NameAcidic phospholipase A2 3
Synonyms3.1.1.4 Phosphatidylcholine 2-acylhydrolase svPLA2
Gene NameNone
OrganismAndaman cobra
Amino acid sequence
>lcl|BSEQ0019715|Acidic phospholipase A2 3
SNRPMPLNLYQFKNMIQCTVPSRSWQDFADYGCYCGKGGSGTPVDDLDRCCQVHDNCYNE
AENISGCRPYFKTYSYECTQGTLTCKGDNNACAASVCDCDRLAAICFAGAPYNDANYNID
LKARCN
Number of residues126
Molecular Weight13968.385
Theoretical pINone
GO Classification
Functions
    calcium ion binding
phospholipase A2 activity
Processes
    phospholipid metabolic process
lipid catabolic process
Components
    extracellular region
General FunctionPhospholipase a2 activity
Specific FunctionPLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Transmembrane Regions
GenBank Protein ID
UniProtKB IDP60045
UniProtKB Entry NamePA2A3_NAJSG
Cellular LocationSecreted
Gene sequence
None
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC ID
Chromosome LocationNone
LocusNone
References
  1. Singh RK, Vikram P, Makker J, Jabeen T, Sharma S, Dey S, Kaur P, Srinivasan A, Singh TP: Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features. Biochemistry. 2003 Oct 14;42(40):11701-6.[14529280 ]
  2. Singh RK, Ethayathulla AS, Jabeen T, Sharma S, Kaur P, Singh TP: Aspirin induces its anti-inflammatory effects through its specific binding to phospholipase A2: crystal structure of the complex formed between phospholipase A2 and aspirin at 1.9 angstroms resolution. J Drug Target. 2005 Feb;13(2):113-9.[15823962 ]

Related FRC

FRCD ID Name Exact Mass Structure




F04772



Aspirin


180.159