Cytochrome c oxidase subunit 6A2, mitochondrial

NameCytochrome c oxidase subunit 6A2, mitochondrial
SynonymsCOX VIa-M COX6A COX6AH COXVIAH Cytochrome c oxidase polypeptide VIa-heart Cytochrome c oxidase subunit VIA-muscle
Gene NameCOX6A2
OrganismHuman
Amino acid sequence
>lcl|BSEQ0017290|Cytochrome c oxidase subunit 6A2, mitochondrial
MALPLRPLTRGLASAAKGGHGGAGARTWRLLTFVLALPSVALCTFNSYLHSGHRPRPEFR
PYQHLRIRTKPYPWGDGNHTLFHNSHVNPLPTGYEHP
Number of residues97
Molecular Weight10815.32
Theoretical pI11.37
GO Classification
Functions
    cytochrome-c oxidase activity
Processes
    generation of precursor metabolites and energy
Components
    mitochondrial respiratory chain complex IV
General FunctionCytochrome-c oxidase activity
Specific FunctionThis protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Transmembrane Regions
GenBank Protein ID180946
UniProtKB IDQ02221
UniProtKB Entry NameCX6A2_HUMAN
Cellular LocationMitochondrion inner membrane
Gene sequence
>lcl|BSEQ0017291|Cytochrome c oxidase subunit 6A2, mitochondrial (COX6A2)
ATGGCTTTGCCTCTGAGGCCCCTGACCCGGGGCTTGGCCAGCGCTGCCAAAGGAGGCCAC
GGAGGAGCAGGAGCTCGTACCTGGCGTCTGCTGACCTTCGTGCTGGCGCTGCCCAGCGTG
GCCCTCTGCACCTTCAACTCCTATCTCCACTCGGGCCACCGCCCGCGCCCCGAGTTCCGT
CCCTACCAACACCTCCGCATCCGCACCAAGCCCTACCCCTGGGGGGACGGCAACCACACT
CTGTTCCACAATAGCCACGTGAACCCTCTGCCCACGGGCTACGAACACCCCTGA
GenBank Gene IDM83308
GeneCard IDNone
GenAtlas ID
HGNC IDHGNC:2279
Chromosome Location16
Locus16p
References
  1. Fabrizi GM, Sadlock J, Hirano M, Mita S, Koga Y, Rizzuto R, Zeviani M, Schon EA: Differential expression of genes specifying two isoforms of subunit VIa of human cytochrome c oxidase. Gene. 1992 Oct 1;119(2):307-12.[1327966 ]
  2. Bachman NJ, Riggs PK, Siddiqui N, Makris GJ, Womack JE, Lomax MI: Structure of the human gene (COX6A2) for the heart/muscle isoform of cytochrome c oxidase subunit VIa and its chromosomal location in humans, mice, and cattle. Genomics. 1997 May 15;42(1):146-51.[9177785 ]
  3. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7.[15489334 ]

Related FRC

FRCD ID Name Exact Mass Structure




F04322



Acetonitrile


41.053




F04324



Acrylonitrile


53.064




F04325



Beta-Aminopropionitrile


70.095




F04326



Benzonitrile


103.124




F04327



Benzeneacetonitrile


117.151




F04332



Chlorfenapyr


407.615




F04333



Chlorothalonil


265.902




F04334



2,6-Dichlorobenzonitrile


172.008




F05174



Thallium


239.83




F03290



Cyanide


26.018




F03919



Linamarin


247.247




F04323



Mandelonitrile


133.15




F04329



Bromoxynil


276.915




F03462



Phosphine


33.998




F02880



Zinc phosphide


264.136




F03880



Methanol


32.042