Keratin-associated protein 5-3

NameKeratin-associated protein 5-3
SynonymsKAP5-9 KAP5.3 Keratin-associated protein 5-9 Keratin-associated protein 5.3 Keratin-associated protein 5.9 KRTAP5-9 KRTAP5.3 KRTAP5.9 UHS KerB-like Ultrahigh sulfur keratin-associated protein 5.3
Gene NameKRTAP5-3
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013128|Keratin-associated protein 5-3
MGCSGCSGGCGSSCGGCGSSCGGCGSGYGGCGSGCCVPVCCCKPVCCCVPACSCSSCGSC
GGSKGVCGSCGGCKGGCGSCGGSKGGCGSSCCVPVCCSSSCGSCGGSKGVCGFRGGSKGG
CGSCGCSQCSCYKPCCCSSGCGSSCCQSSCCKPSCSQSSCCKPCCSQSSCCKPCCCSSGC
GSSCCQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCSSQSSCCVPICCQCKI
Number of residues238
Molecular Weight22105.295
Theoretical pINone
GO Classification
Functions

                

              
Processes

                

                    

                

              
Components

                

                  
    keratin filament

                

              

          		
      

      
General FunctionNone

      
Specific FunctionIn the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

      
Transmembrane Regions

      
GenBank Protein ID

      
UniProtKB IDQ6L8H2  

      
UniProtKB Entry NameKRA53_HUMAN  

      
Cellular LocationNone

      
Gene sequence
>lcl|BSEQ0013129|Keratin-associated protein 5-3 (KRTAP5-3)
ATGGGCTGCTCTGGCTGCTCTGGAGGCTGTGGCTCCAGCTGTGGGGGCTGTGGCTCCAGC
TGTGGGGGCTGTGGCTCCGGCTATGGGGGCTGTGGCTCCGGCTGCTGTGTACCTGTCTGC
TGCTGCAAGCCCGTGTGCTGCTGTGTGCCAGCCTGTTCCTGCTCCAGCTGTGGCTCCTGT
GGGGGCTCCAAGGGGGTCTGTGGCTCTTGTGGGGGCTGCAAGGGGGGCTGTGGCTCCTGT
GGAGGCTCCAAGGGGGGCTGTGGCTCCAGCTGCTGTGTGCCCGTCTGCTGCTCCTCCAGC
TGTGGCTCCTGTGGGGGTTCCAAGGGGGTCTGTGGATTTCGTGGGGGCTCCAAGGGGGGC
TGCGGTTCTTGTGGCTGCTCCCAGTGCAGCTGCTATAAGCCCTGCTGCTGCTCCTCAGGC
TGTGGGTCATCCTGCTGCCAGTCCAGCTGCTGCAAGCCCAGCTGCTCCCAGTCCAGCTGC
TGTAAGCCCTGCTGTTCCCAGTCCAGCTGCTGTAAGCCCTGCTGCTGCTCCTCAGGCTGT
GGGTCATCCTGCTGCCAGTCCAGCTGCTGCAAACCCTGCTGTTCCCAGTCCAGCTGCTGT
AAGCCCTGCTGCTGCTCCTCAGGCTGTGGGTCATCCTGCTGCCAGTCCAGCTGCTGCAAG
CCCTGCTCCTCCCAGTCCAGCTGCTGTGTCCCAATTTGCTGCCAGTGCAAGATCTGA

      
GenBank Gene ID

      
GeneCard IDNone

      
GenAtlas ID

      
HGNC IDHGNC:23598  

      
Chromosome Location11

      
LocusNone

      
References
        
          
    
            
            
  1. Yahagi S, Shibuya K, Obayashi I, Masaki H, Kurata Y, Kudoh J, Shimizu N: Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11. Biochem Biophys Res Commun. 2004 Jun 4;318(3):655-64.[15144888  ]
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Related FRC

      

    

    
        

            FRCD ID
            Name
            Exact Mass
            
            Structure
        

        
        

        
        

            
                

                



F05350
                

            		
            


D-Glucose

            


180.156