Aquaporin-12A

NameAquaporin-12A
SynonymsAQP-12 AQP12 AQPX2
Gene NameAQP12A
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013390|Aquaporin-12A
MAGLNVSLSFFFATFALCEAARRASKALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLL
LTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLC
WAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAV
ALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLHQG
RLPHLFQRNLFYGQKNKYRAPRGKPAPASGDTQTPAKGSSVREPGRSGVEGPHSS
Number of residues295
Molecular Weight31474.21
Theoretical pINone
GO Classification
Functions
    transporter activity
Processes

                

              
Components

                

                  
    integral component of membrane

                

              

          		
      

      
General FunctionTransporter activity

      
Specific FunctionAquaporins facilitate the transport of water and small neutral solutes across cell membranes.

      
Transmembrane Regions1-21
55-75
100-126
146-166
179-199
216-236

      
GenBank Protein ID

      
UniProtKB IDQ8IXF9  

      
UniProtKB Entry NameAQ12A_HUMAN  

      
Cellular LocationMembrane

      
Gene sequence
>lcl|BSEQ0013391|Aquaporin-12A (AQP12A)
ATGGCAGGTCTTAACGTGTCCCTCTCCTTCTTCTTTGCCACCTTCGCCCTCTGTGAGGCG
GCCAGGCGGGCCTCCAAGGCCCTGCTCCCAGTGGGCGCCTATGAAGTCTTCGCCCGGGAG
GCGATGAGGACGCTGGTCGAGCTCGGGCCCTGGGCTGGGGACTTTGGGCCTGACCTGCTG
CTCACCCTGCTCTTCCTGCTCTTCCTGGCGCACGGGGTCACCTTGGACGGGGCCTCGGCC
AACCCCACTGTGTCCCTGCAGGAGTTCCTCATGGCCGAGCAGTCTCTGCCTGGCACGCTG
TTGAAGCTGGCGGCACAGGGGCTGGGCATGCAGGCCGCCTGCACCCTGATGCGCCTCTGC
TGGGCCTGGGAGCTCAGTGACCTGCACCTGCTGCAGAGCCTCATGGCCCAGAGCTGCAGC
TCGGCCCTGCGCACATCCGTGCCCCACGGGGCGCTTGTGGAGGCCGCCTGCGCCTTTTGT
TTCCATCTGACCCTCCTGCACCTGCGGCACAGTCCTCCCGCCTACAGCGGGCCCGCTGTG
GCTCTGTTGGTCACCGTCACGGCCTACACGGCCGGGCCCTTCACGTCTGCCTTCTTCAAC
CCTGCCCTGGCCGCCTCTGTGACCTTTGCCTGCTCGGGACACACCTTACTGGAGTACGTG
CAGGTGTACTGGCTGGGCCCTCTGACAGGGATGGTCCTGGCTGTGCTGCTGCACCAGGGC
CGCCTTCCCCACCTTTTCCAGAGGAACCTGTTCTACGGCCAGAAGAACAAGTACCGAGCA
CCCCGAGGGAAGCCGGCCCCGGCCTCAGGGGACACCCAGACCCCTGCAAAGGGGTCCAGT
GTCCGGGAGCCTGGGCGCAGTGGTGTTGAGGGGCCACATTCCAGCTGA

      
GenBank Gene ID

      
GeneCard IDNone

      
GenAtlas ID

      
HGNC IDHGNC:19941  

      
Chromosome Location2

      
LocusNone

      
References
        
          
    
            
            
  1. Itoh T, Rai T, Kuwahara M, Ko SB, Uchida S, Sasaki S, Ishibashi K: Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells. Biochem Biophys Res Commun. 2005 May 13;330(3):832-8.[15809071  ]
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Related FRC

      

    

    
        

            FRCD ID
            Name
            Exact Mass
            
            Structure
        

        
        

        
        

            
                

                



F03269
                

            		
            


Mercury

            


200.592		
            
        

        
        

            
                

                



F02629
                

            		
            


Mercuric chloride

            


271.492		
            
        

        
        

            
                

                



F02987
                

            		
            


Methylmercuric chloride

            


252.085		
            
        

        
        

            
                

                



F04213
                

            		
            


Mercurol

            


252.668		
            
        

        
        

            
                

                



F04214
                

            		
            


Mercaptomerin

            


606.009		
            
        

        
        

            
                

                



F04217
                

            		
            


Meralluride

            


449.835		
            
        

        
        

            
                

                



F04218
                

            		
            


Merbromin

            


751.666		
            
        

        
        

            
                

                



F04221
                

            		
            


Thiomersal

            


404.811