Voltage-dependent calcium channel gamma-like subunit

NameVoltage-dependent calcium channel gamma-like subunit
SynonymsNeuronal voltage-gated calcium channel gamma-like subunit PR Transmembrane protein 37
Gene NameTMEM37
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013469|Voltage-dependent calcium channel gamma-like subunit
MTAVGVQAQRPLGQRQPRRSFFESFIRTLIITCVALAVVLSSVSICDGHWLLAEDRLFGL
WHFCTTTNQTICFRDLGQAHVPGLAVGMGLVRSVGALAVVAAIFGLEFLMVSQLCEDKHS
QCKWVMGSILLLVSFVLSSGGLLGFVILLRNQVTLIGFTLMFWCEFTASFLLFLNAISGL
HINSITHPWE
Number of residues190
Molecular Weight20931.565
Theoretical pINone
GO Classification
Functions
    voltage-gated ion channel activity
calcium channel activity
Processes

                

              
Components

                

                  
    integral component of membrane

                

              

          		
      

      
General FunctionVoltage-gated ion channel activity

      
Specific FunctionThought to stabilize the calcium channel in an inactivated (closed) state. Modulates calcium current when coexpressed with CACNA1G (By similarity).

      
Transmembrane Regions25-45
96-116
131-151
155-175

      
GenBank Protein ID

      
UniProtKB IDQ8WXS4  

      
UniProtKB Entry NameCCGL_HUMAN  

      
Cellular LocationMembrane

      
Gene sequence
>lcl|BSEQ0013470|Voltage-dependent calcium channel gamma-like subunit (TMEM37)
ATGACTGCCGTCGGCGTGCAGGCCCAGAGGCCTTTGGGCCAAAGGCAGCCCCGCCGGTCC
TTCTTTGAATCCTTCATCCGGACCCTCATCATCACGTGTGTGGCCCTGGCTGTGGTCCTG
TCCTCGGTCTCCATTTGTGATGGGCACTGGCTCCTGGCTGAGGACCGCCTCTTCGGGCTC
TGGCACTTCTGCACCACCACCAACCAGACGATCTGCTTCAGAGACCTGGGCCAGGCCCAT
GTGCCCGGGCTGGCCGTGGGCATGGGCCTGGTACGCAGCGTGGGCGCCTTGGCCGTGGTG
GCCGCCATTTTTGGCCTGGAGTTCCTCATGGTGTCCCAGTTGTGCGAGGACAAACACTCA
CAGTGCAAGTGGGTCATGGGTTCCATCCTCCTCCTGGTGTCTTTCGTCCTCTCCTCCGGC
GGGCTCCTGGGTTTTGTGATCCTCCTCAGGAACCAAGTCACACTCATCGGCTTCACCCTA
ATGTTTTGGTGCGAATTCACTGCCTCCTTCCTCCTCTTCCTGAACGCCATCAGCGGCCTT
CACATCAACAGCATCACCCATCCCTGGGAATGA

      
GenBank Gene ID

      
GeneCard IDNone

      
GenAtlas ID

      
HGNC IDHGNC:18216  

      
Chromosome Location2

      
LocusNone

      
References
        
          
    
            
            
  1. Chu PJ, Robertson HM, Best PM: Calcium channel gamma subunits provide insights into the evolution of this gene family. Gene. 2001 Dec 12;280(1-2):37-48.[11738816  ]
    2. 
            
            
  2. Hillier LW, Graves TA, Fulton RS, Fulton LA, Pepin KH, Minx P, Wagner-McPherson C, Layman D, Wylie K, Sekhon M, Becker MC, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Kremitzki C, Oddy L, Du H, Sun H, Bradshaw-Cordum H, Ali J, Carter J, Cordes M, Harris A, Isak A, van Brunt A, Nguyen C, Du F, Courtney L, Kalicki J, Ozersky P, Abbott S, Armstrong J, Belter EA, Caruso L, Cedroni M, Cotton M, Davidson T, Desai A, Elliott G, Erb T, Fronick C, Gaige T, Haakenson W, Haglund K, Holmes A, Harkins R, Kim K, Kruchowski SS, Strong CM, Grewal N, Goyea E, Hou S, Levy A, Martinka S, Mead K, McLellan MD, Meyer R, Randall-Maher J, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Shah N, Swearengen-Shahid S, Snider J, Strong JT, Thompson J, Yoakum M, Leonard S, Pearman C, Trani L, Radionenko M, Waligorski JE, Wang C, Rock SM, Tin-Wollam AM, Maupin R, Latreille P, Wendl MC, Yang SP, Pohl C, Wallis JW, Spieth J, Bieri TA, Berkowicz N, Nelson JO, Osborne J, Ding L, Meyer R, Sabo A, Shotland Y, Sinha P, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Jones TA, She X, Ciccarelli FD, Izaurralde E, Taylor J, Schmutz J, Myers RM, Cox DR, Huang X, McPherson JD, Mardis ER, Clifton SW, Warren WC, Chinwalla AT, Eddy SR, Marra MA, Ovcharenko I, Furey TS, Miller W, Eichler EE, Bork P, Suyama M, Torrents D, Waterston RH, Wilson RK: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. Nature. 2005 Apr 7;434(7034):724-31.[15815621  ]
    3. 
            
          

        		
      

    

    


      
    
Related FRC

      

    

    
        

            FRCD ID
            Name
            Exact Mass
            
            Structure
        

        
        

        
        

            
                

                



F03806
                

            		
            


Cobaltocene

            


189.123		
            
        

        
        

            
                

                



F03807
                

            		
            


Adenosylcobalamin

            


1579.608		
            
        

        
        

            
                

                



F03808
                

            		
            


Cyanocobalamin

            


1356.396		
            
        

        
        

            
                

                



F03812
                

            		
            


Hydroxocobalamin

            


1346.377		
            
        

        
        

            
                

                



F03814
                

            		
            


Methylcobalamin

            


1344.405		
            
        

        
        

            
                

                



F03815
                

            		
            


Salcomine

            


327.249