Protamine-3

NameProtamine-3
SynonymsSperm protamine P3
Gene NamePRM3
OrganismHuman
Amino acid sequence
>lcl|BSEQ0013455|Protamine-3
MGSRCAKLNTGQSPGHSPGHSTGHGRGHESSMKKLMACVSQDNFSLSSAGEEEEEEEEEG
EEEEKEELPVQGKLLLLEPERQEEGQKDNAEAQQSPEPKQTPS
Number of residues103
Molecular Weight11232.01
Theoretical pINone
GO Classification
Functions
    DNA binding
Processes
    chromosome condensation
cell differentiation
multicellular organismal development
sperm motility
spermatogenesis
Components
    cytoplasm
nucleus
nucleosome
General FunctionDna binding
Specific FunctionProtamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
Transmembrane Regions
GenBank Protein ID
UniProtKB IDQ9NNZ6
UniProtKB Entry NamePRM3_HUMAN
Cellular LocationNucleus
Gene sequence
None
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC IDHGNC:13732
Chromosome LocationNone
LocusNone
References
  1. Schluter G, Celik A, Obata R, Schlicker M, Hofferbert S, Schlung A, Adham IM, Engel W: Sequence analysis of the conserved protamine gene cluster shows that it contains a fourth expressed gene. Mol Reprod Dev. 1996 Jan;43(1):1-6.[8720108 ]

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