Potassium voltage-gated channel subfamily H member 3
| Name | Potassium voltage-gated channel subfamily H member 3 |
|---|---|
| Synonyms | BEC1 Brain-specific eag-like channel 1 ELK channel 2 ELK2 Ether-a-go-go-like potassium channel 2 KIAA1282 Voltage-gated potassium channel subunit Kv12.2 |
| Gene Name | KCNH3 |
| Organism | Human |
| Amino acid sequence | >lcl|BSEQ0008967|Potassium voltage-gated channel subfamily H member 3 MPAMRGLLAPQNTFLDTIATRFDGTHSNFVLGNAQVAGLFPVVYCSDGFCDLTGFSRAEV MQRGCACSFLYGPDTSELVRQQIRKALDEHKEFKAELILYRKSGLPFWCLLDVIPIKNEK GEVALFLVSHKDISETKNRGGPDRWKETGGGRRRYGRARSKGFNANRRRSRAVLYHLSGH LQKQPKGKHKLNKGVFGEKPNLPEYKVAAIRKSPFILLHCGALRATWDGFILLATLYVAV TVPYSVCVSTAREPSAARGPPSVCDLAVEVLFILDIVLNFRTTFVSKSGQVVFAPKSICL HYVTTWFLLDVIAALPFDLLHAFKVNVYFGAHLLKTVRLLRLLRLLPRLDRYSQYSAVVL TLLMAVFALLAHWVACVWFYIGQREIESSESELPEIGWLQELARRLETPYYLVGRRPAGG NSSGQSDNCSSSSEANGTGLELLGGPSLRSAYITSLYFALSSLTSVGFGNVSANTDTEKI FSICTMLIGALMHAVVFGNVTAIIQRMYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLE YFQATWAVNNGIDTTELLQSLPDELRADIAMHLHKEVLQLPLFEAASRGCLRALSLALRP AFCTPGEYLIHQGDALQALYFVCSGSMEVLKGGTVLAILGKGDLIGCELPRREQVVKANA DVKGLTYCVLQCLQLAGLHDSLALYPEFAPRFSRGLRGELSYNLGAGGGSAEVDTSSLSG DNTLMSTLEEKETDGEQGPTVSPAPADEPSSPLLSPGCTSSSSAAKLLSPRRTAPRPRLG GRGRPGRAGALKAEAGPSAPPRALEGLRLPPMPWNVPPDLSPRVVDGIEDGCGSDQPKFS FRVGQSGPECSSSPSPGPESGLLTVPHGPSEARNTDTLDKLRQAVTELSEQVLQMREGLQ SLRQAVQLVLAPHREGPCPRASGEGPCPASTSGLLQPLCVDTGASSYCLQPPAGSVLSGT WPHPRPGPPPLMAPWPWGPPASQSSPWPRATAFWTSTSDSEPPASGDLCSEPSTPASPPP SEEGARTGPAEPVSQAEATSTGEPPPGSGGLALPWDPHSLEMVLIGCHGSGTVQWTQEEG TGV |
| Number of residues | 1083 |
| Molecular Weight | 117127.74 |
| Theoretical pI | None |
| GO Classification |
Functions
phosphorelay sensor kinase activity voltage-gated potassium channel activity Processes
regulation of membrane potential potassium ion transport synaptic transmission potassium ion transmembrane transport Components
intracellular plasma membrane integral component of membrane integral component of plasma membrane |
| General Function | Voltage-gated potassium channel activity |
| Specific Function | Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP and subunit assembly. |
| Transmembrane Regions | 229-249 260-280 303-323 332-352 362-382 480-500 |
| GenBank Protein ID | |
| UniProtKB ID | Q9ULD8 |
| UniProtKB Entry Name | KCNH3_HUMAN |
| Cellular Location | Membrane |
| Gene sequence | >lcl|BSEQ0021432|Potassium voltage-gated channel subfamily H member 3 (KCNH3) ATGCCGGCCATGCGGGGCCTCCTGGCGCCGCAGAACACCTTCCTGGACACCATCGCTACG CGCTTCGACGGCACGCACAGTAACTTCGTGCTGGGCAACGCCCAGGTGGCGGGGCTCTTC CCCGTGGTCTACTGCTCTGATGGCTTCTGTGACCTCACGGGCTTCTCCCGGGCTGAGGTC ATGCAGCGGGGCTGTGCCTGCTCCTTCCTTTATGGGCCAGACACCAGTGAGCTCGTCCGC CAACAGATCCGCAAGGCCCTGGACGAGCACAAGGAGTTCAAGGCTGAGCTGATCCTGTAC CGGAAGAGCGGGCTCCCGTTCTGGTGTCTCCTGGATGTGATACCCATAAAGAATGAGAAA GGGGAGGTGGCTCTCTTCCTAGTCTCTCACAAGGACATCAGCGAAACCAAGAACCGAGGG GGCCCCGACAGATGGAAGGAGACAGGTGGTGGCCGGCGCCGATATGGCCGGGCACGATCC AAAGGCTTCAATGCCAACCGGCGGCGGAGCCGGGCCGTGCTCTACCACCTGTCCGGGCAC CTGCAGAAGCAGCCCAAGGGCAAGCACAAGCTCAATAAGGGGGTGTTTGGGGAGAAACCA AACTTGCCTGAGTACAAAGTAGCCGCCATCCGGAAGTCGCCCTTCATCCTGTTGCACTGT GGGGCACTGAGAGCCACCTGGGATGGCTTCATCCTGCTCGCCACACTCTATGTGGCTGTC ACTGTGCCCTACAGCGTGTGTGTGAGCACAGCACGGGAGCCCAGTGCCGCCCGCGGCCCG CCCAGCGTCTGTGACCTGGCCGTGGAGGTCCTCTTCATCCTTGACATTGTGCTGAATTTC CGTACCACATTCGTGTCCAAGTCGGGCCAGGTGGTGTTTGCCCCAAAGTCCATTTGCCTC CACTACGTCACCACCTGGTTCCTGCTGGATGTCATCGCAGCGCTGCCCTTTGACCTGCTA CATGCCTTCAAGGTCAACGTGTACTTCGGGGCCCATCTGCTGAAGACGGTGCGCCTGCTG CGCCTGCTGCGCCTGCTTCCGCGGCTGGACCGGTACTCGCAGTACAGCGCCGTGGTGCTG ACACTGCTCATGGCCGTGTTCGCCCTGCTCGCGCACTGGGTCGCCTGCGTCTGGTTTTAC ATTGGCCAGCGGGAGATCGAGAGCAGCGAATCCGAGCTGCCTGAGATTGGCTGGCTGCAG GAGCTGGCCCGCCGACTGGAGACTCCCTACTACCTGGTGGGCCGGAGGCCAGCTGGAGGG AACAGCTCCGGCCAGAGTGACAACTGCAGCAGCAGCAGCGAGGCCAACGGGACGGGGCTG GAGCTGCTGGGCGGCCCGTCGCTGCGCAGCGCCTACATCACCTCCCTCTACTTCGCACTC AGCAGCCTCACCAGCGTGGGCTTCGGCAACGTGTCCGCCAACACGGACACCGAGAAGATC TTCTCCATCTGCACCATGCTCATCGGCGCCCTGATGCACGCGGTGGTGTTTGGGAACGTG ACGGCCATCATCCAGCGCATGTACGCCCGCCGCTTTCTGTACCACAGCCGCACGCGCGAC CTGCGCGACTACATCCGCATCCACCGTATCCCCAAGCCCCTCAAGCAGCGCATGCTGGAG TACTTCCAGGCCACCTGGGCGGTGAACAATGGCATCGACACCACCGAGCTGCTGCAGAGC CTCCCTGACGAGCTGCGCGCAGACATCGCCATGCACCTGCACAAGGAGGTCCTGCAGCTG CCACTGTTTGAGGCGGCCAGCCGCGGCTGCCTGCGGGCACTGTCTCTGGCCCTGCGGCCC GCCTTCTGCACGCCGGGCGAGTACCTCATCCACCAAGGCGATGCCCTGCAGGCCCTCTAC TTTGTCTGCTCTGGCTCCATGGAGGTGCTCAAGGGTGGCACCGTGCTCGCCATCCTAGGG AAGGGCGACCTGATCGGCTGTGAGCTGCCCCGGCGGGAGCAGGTGGTAAAGGCCAATGCC GACGTGAAGGGGCTGACGTACTGCGTCCTGCAGTGTCTGCAGCTGGCTGGCCTGCACGAC AGCCTTGCGCTGTACCCCGAGTTTGCCCCGCGCTTCAGTCGTGGCCTCCGAGGGGAGCTC AGCTACAACCTGGGTGCTGGGGGAGGCTCTGCAGAGGTGGACACCAGCTCCCTGAGCGGC GACAATACCCTTATGTCCACGCTGGAGGAGAAGGAGACAGATGGGGAGCAGGGCCCCACG GTCTCCCCAGCCCCAGCTGATGAGCCCTCCAGCCCCCTGCTGTCCCCTGGCTGCACCTCC TCATCCTCAGCTGCCAAGCTGCTATCCCCACGTCGAACAGCACCCCGGCCTCGTCTAGGT GGCAGAGGGAGGCCAGGCAGGGCAGGGGCTTTGAAGGCTGAGGCTGGCCCCTCTGCTCCC CCACGGGCCCTAGAGGGGCTACGGCTGCCCCCCATGCCATGGAATGTGCCCCCAGATCTG AGCCCCAGGGTAGTAGATGGCATTGAAGACGGCTGTGGCTCGGACCAGCCCAAGTTCTCT TTCCGCGTGGGCCAGTCTGGCCCGGAATGTAGCAGCAGCCCCTCCCCTGGACCAGAGAGC GGCCTGCTCACTGTTCCCCATGGGCCCAGCGAGGCAAGGAACACAGACACACTGGACAAG CTTCGGCAGGCGGTGACAGAGCTGTCAGAGCAGGTGCTGCAGATGCGGGAAGGACTGCAG TCACTTCGCCAGGCTGTGCAGCTTGTCCTGGCGCCCCACAGGGAGGGTCCGTGCCCTCGG GCATCGGGAGAGGGGCCGTGCCCAGCCAGCACCTCCGGGCTTCTGCAGCCTCTGTGTGTG GACACTGGGGCATCCTCCTACTGCCTGCAGCCCCCAGCTGGCTCTGTCTTGAGTGGGACT TGGCCCCACCCTCGTCCGGGGCCTCCTCCCCTCATGGCACCCTGGCCCTGGGGTCCCCCA GCGTCTCAGAGCTCCCCCTGGCCTCGAGCCACAGCTTTCTGGACCTCCACCTCAGACTCA GAGCCCCCTGCCTCAGGAGACCTCTGCTCTGAGCCCAGCACCCCTGCCTCCCCTCCTCCT TCTGAGGAAGGGGCTAGGACTGGGCCCGCAGAGCCTGTGAGCCAGGCTGAGGCTACCAGC ACTGGAGAGCCCCCACCAGGGTCAGGGGGCCTGGCCTTGCCCTGGGACCCCCACAGCCTG GAGATGGTGCTTATTGGCTGCCATGGCTCTGGCACAGTCCAGTGGACCCAGGAAGAAGGC ACAGGGGTCTGA |
| GenBank Gene ID | |
| GeneCard ID | None |
| GenAtlas ID | |
| HGNC ID | HGNC:6252 |
| Chromosome Location | 12 |
| Locus | None |
| References |
|
Related FRC
| FRCD ID | Name | Exact Mass | Structure |
|---|---|---|---|
Cesium |
132.905 |
||
Barium |
137.327 |