Natural products: Sponge symbionts play defense来源： 时间：七月 21, 2014, 9:55 a.m.
The gene cluster that produces the sponge-derived cytotoxin calyculin A has been located in an uncultivated bacterial symbiont. Biochemical analyses reveal a pyrophosphorylated protoxin as the true biosynthetic product and suggest that calyculins result from activated chemical defense.
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