Natural products: Sponge symbionts play defense
来源: 时间:July 21, 2014, 9:55 a.m.http://www.nature.com/nchembio/journal/v10/n8/full/nchembio.1588.html?WT.ec_id=NCHEMBIO-201408
The gene cluster that produces the sponge-derived cytotoxin calyculin A has been located in an uncultivated bacterial symbiont. Biochemical analyses reveal a pyrophosphorylated protoxin as the true biosynthetic product and suggest that calyculins result from activated chemical defense.
上一篇:A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity
下一篇:Nature Methods: Focus on Synthetic Biology