POLYETHYLENE GLYCOL (M W 200-9,500)
Relevant Data
Food Additives Approved by WHO:
Food Additives Approved by European Union:
General Information
| Mainterm | POLYETHYLENE GLYCOL (M W 200-9,500) |
| Doc Type | ASP |
| CAS Reg.No.(or other ID) | 25322-68-3 |
| Regnum |
175.105 175.300 176.180 172.820 73.1 173.310 173.340 172.210 178.3750 |
From www.fda.gov
Targets
- General Function:
- Zinc ion binding
- Specific Function:
- By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.
- Gene Name:
- ENPP1
- Uniprot ID:
- P22413
- Molecular Weight:
- 104923.58 Da
From T3DB