VITAMIN D
General Information
Mainterm | VITAMIN D |
Doc Type | ASP |
CAS Reg.No.(or other ID) | 1406-16-2 |
Regnum |
166.110 101.9 107.100 137.260 137.305 137.350 139.115 139.155 131.110 131.115 131.123 131.127 131.135 131.143 131.147 131.111 131.112 131.200 131.203 131.206 107.10 184.1950 |
From www.fda.gov
Targets
- General Function:
- Zinc ion binding
- Specific Function:
- Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
- Gene Name:
- VDR
- Uniprot ID:
- P11473
- Molecular Weight:
- 48288.64 Da
- General Function:
- Vitamin transporter activity
- Specific Function:
- Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
- Gene Name:
- GC
- Uniprot ID:
- P02774
- Molecular Weight:
- 52963.025 Da
From T3DB