BETAINE
General Information
| Mainterm | BETAINE |
| Doc Type | EAF |
| CAS Reg.No.(or other ID) | 107-43-7 |
| Regnum |
From www.fda.gov
Targets
- General Function:
- Ubiquitin protein ligase binding
- Specific Function:
- Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
- Gene Name:
- BCL2
- Uniprot ID:
- P10415
- Molecular Weight:
- 26265.66 Da
From T3DB