Sodium carbonates

Relevant Data

Food Additives Approved in the United States

Food Additives Approved by WHO:

General Information

Chemical nameSodium carbonates
E No.E 500
INS.500
CAS number497-19-8
GroupNo
Component of the group Group I, Additives (Group I)
Carbonates (E 500 - 504)

From webgate.ec.europa.eu

Authorisation of the use of this additive in Food Additives

The additive is authorised to be used in the following category(ies):
category(ies) Individual restriction(s)/exception(s) footnote
  • Table-Top Sweeteners in liquid form (11.4.1)(legislation:1129/2011, applicable as from 01/06/2013)

  • Table-Top Sweeteners in powder form (11.4.2)(legislation:1129/2011, applicable as from 01/06/2013)

  • Table-Top Sweeteners in tablets (11.4.3)(legislation:1129/2011, applicable as from 01/06/2013)

  • Salt (12.1.1)(legislation:1129/2011, applicable as from 01/06/2013)

  • Other foods for young children (13.1.4)(legislation:1129/2011, applicable as from 01/06/2013)
  • quantum satis
  • Butter and concentrated butter and butter oil and anhydrous milkfat (2.2.1)(legislation:1129/2011, applicable as from 01/06/2013)
  • quantum satis , only soured cream butter
  • Processed cereal-based foods and baby foods for infants and young children as defined by Directive 2006/125/EC (13.1.3)(legislation:1129/2011, applicable as from 01/06/2013)

  • Dietary foods for infants for special medical purposes and special formulae for infants (13.1.5.1)(legislation:1129/2011, applicable as from 01/06/2013)
  • quantum satis , only as rising agent
  • Meat preparations as defined by Regulation (EC) No 853/2004 (8.2)(legislation:601/2014, applicable as from 25/06/2014)
  • quantum satis , only poultry meat preparations, mici, bifteki, soutzoukaki, kebap, seftalia, ćevapčići and pljeskavice

From webgate.ec.europa.eu

Computed Descriptors

Download SDF
2D Structure
CID10340
IUPAC Namedisodium;carbonate
InChIInChI=1S/CH2O3.2Na/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
InChI KeyCDBYLPFSWZWCQE-UHFFFAOYSA-L
Canonical SMILESC(=O)([O-])[O-].[Na+].[Na+]
Molecular FormulaNa2CO3· nH2O (n = 0, 1 or 10)
Wikipediasodium carbonate

From Pubchem

Computed Properties

Property Name Property Value
Molecular Weight105.988
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Complexity18.8
CACTVS Substructure Key Fingerprint A A A D c Q A A M D A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A g A A A A A A A A A A A A A A C A A A A A A I A A A A C A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A = =
Topological Polar Surface Area63.2
Monoisotopic Mass105.964
Exact Mass105.964
Compound Is CanonicalizedTrue
Formal Charge0
Heavy Atom Count6
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Isotope Atom Count0
Covalently-Bonded Unit Count3

From Pubchem

Taxonomic Classification

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassOrganic carbonic acids and derivatives
SubclassOrganic carbonic acids
Intermediate Tree NodesNot available
Direct ParentOrganic carbonic acids
Alternative Parents
Molecular FrameworkAliphatic acyclic compounds
SubstituentsCarbonate salt - Carbonic acid - Organic alkali metal salt - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organic sodium salt - Organic salt - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as organic carbonic acids. These are compounds comprising the carbonic acid functional group.

From ClassyFire

Targets

Target Details

Carbonic anhydrase 1

General Function:
Zinc ion binding
Specific Function:
Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
Gene Name:
CA1
Uniprot ID:
P00915
Molecular Weight:
28870.0 Da
Target Details

Carbonic anhydrase 2

General Function:
Zinc ion binding
Specific Function:
Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.
Gene Name:
CA2
Uniprot ID:
P00918
Molecular Weight:
29245.895 Da
Target Details

Carbonic anhydrase 4

General Function:
Zinc ion binding
Specific Function:
Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid.
Gene Name:
CA4
Uniprot ID:
P22748
Molecular Weight:
35032.075 Da
Target Details

Carbonic anhydrase 9

General Function:
Zinc ion binding
Specific Function:
Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
Gene Name:
CA9
Uniprot ID:
Q16790
Molecular Weight:
49697.36 Da

From T3DB