3-PHYTASE FROM ASPERGILLUS NIGER EXPRESSED IN ASPERGILLUS NIGER
General Information
Chemical Names: | 3-phytase: myo-inositol hexakisphosphate 3-phosphohydrolase (EC 3.1.3.8) |
Functional Class: |
Food Additives ENZYME_PREPARATION |
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Evaluations
Evaluation year: | 2012 |
ADI: | NOT SPECIFIED |
Specs Code: | N |
Comments: | Comparing the conservative exposure estimate with the no-observed-adverse-effect level (NOAEL) from the 13-week study of oral toxicity in rats, the margin of exposure is approximately 250. The Committee allocated an ADI “not specified”b for 3-phytase enzyme preparation from A. niger expressed in A. niger used in the applications specified and in accordance with good manufacturing practice. |
Report: | TRS 974 JECFA 76 |
Tox Monograph: | FAS 67 JECFA 76 |
Specification: | Compendium of food additive specifications. FAO JECFA Monographs 13, 2012 |
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