CALCIUM CYCLAMATE

General Information

Chemical Names: CALCIUM CYCLOHEXANESULFAMATE; CALCIUM CYCLOHEXYLSULFAMATE
CAS number: 139-06-0
INS:

952(ii)
Functional Class: Food Additives
SWEETENER

From apps.who.int

Evaluations

Evaluation year: 1982
ADI: 0-11 mg/kg bw
Meeting: 46
Specs Code: R (1996)
Comments: CYCLAMATES ADI EXPRESSED AS CYCLAMIC ACID
Report: TRS 683-JECFA 26/27
Tox Monograph: FAS 17-JECFA 26/66
Specification: COMPENDIUM ADDENDUM 12/FNP 52 Add. 12/67 (METALS LIMITS) (2004); ; FAO JECFA Monographs 1 vol.1/221

From apps.who.int

GSFA Provisions for CALCIUM CYCLAMATE

Number Food Category Max Level Notes
14.2.7

Aromatized alcoholic beverages (e.g. beer, wine and spirituous cooler-type beverages, low alcoholic refreshers)

 250 mg/kg Note 17
04.1.2.4

Canned or bottled (pasteurized) fruit

 1,000 mg/kg Note 17,Note 161
06.5

Cereal and starch based desserts (e.g. rice pudding, tapioca pudding)

 250 mg/kg Note 17,Note 161
05.3

Chewing gum

 3,000 mg/kg Note 17,Note 161
05.1.4

Cocoa and chocolate products

 500 mg/kg Note 17,Note 161
05.1.2

Cocoa mixes (syrups)

 250 mg/kg Note 17,Note 127,Note 161
05.1.3

Cocoa-based spreads, including fillings

 500 mg/kg Note 17,Note XS86,Note 161
14.1.3.3

Concentrates for fruit nectar

 400 mg/kg Note 17,Note 127,Note 122
14.1.3.4

Concentrates for vegetable nectar

 400 mg/kg Note 17,Note 127,Note 161
05.2

Confectionery including hard and soft candy, nougats, etc. other than food categories 05.1, 05.3 and 05.4

 500 mg/kg Note 17,Note 156,Note XS309R,Note 161
01.7

Dairy-based desserts (e.g. pudding, fruit or flavoured yoghurt)

 250 mg/kg Note 17,Note 161
05.4

Decorations (e.g. for fine bakery wares), toppings (non-fruit) and sweet sauces

 500 mg/kg Note 17,Note 161
13.5

Dietetic foods (e.g. supplementary foods for dietary use) excluding products of food categories 13.1 - 13.4 and 13.6

 400 mg/kg Note 17
13.3

Dietetic foods intended for special medical purposes (excluding products of food category 13.1)

 400 mg/kg Note 17
13.4

Dietetic formulae for slimming purposes and weight reduction

 400 mg/kg Note 17
03.0

Edible ices, including sherbet and sorbet

 250 mg/kg Note 17,Note 161
10.4

Egg-based desserts (e.g. custard)

 250 mg/kg Note 17,Note 161
12.6.1

Emulsified sauces and dips (e.g. mayonnaise, salad dressing, onion dip)

 500 mg/kg Note 17,Note 161
02.4

Fat-based desserts excluding dairy-based dessert products of food category 01.7

 250 mg/kg Note 17,Note 161
07.2

Fine bakery wares (sweet, salty, savoury) and mixes

 1,600 mg/kg Note 17,Note 165
01.1.4

Flavoured fluid milk drinks

 250 mg/kg Note 17,Note 161
13.6

Food supplements

 1,250 mg/kg Note 17
14.1.3.1

Fruit nectar

 400 mg/kg Note 122,Note 17
04.1.2.8

Fruit preparations, including pulp, purees, fruit toppings and coconut milk

 250 mg/kg Note 17,Note 161
04.1.2.9

Fruit-based desserts, including fruit-flavoured water-based desserts

 250 mg/kg Note 17,Note 161
04.1.2.6

Fruit-based spreads (e.g. chutney) excluding products of food category 04.1.2.5

 2,000 mg/kg Note 17,Note 161
05.1.5

Imitation chocolate, chocolate substitute products

 500 mg/kg Note 17,Note 161
04.1.2.5

Jams, jellies, marmelades

 1,000 mg/kg Note 17,Note 161
11.4

Other sugars and syrups (e.g. xylose, maple syrup, sugar toppings)

 500 mg/kg Note 17,Note 159
12.7

Salads (e.g. macaroni salad, potato salad) and sandwich spreads excluding cocoa- and nut-based spreads of food categories 04.2.2.5 and 05.1.3

 500 mg/kg Note 17,Note 161
11.6

Table-top sweeteners, including those containing high-intensity sweeteners

 GMP Note 17
04.2.2.6

Vegetable (including mushrooms and fungi, roots and tubers, pulses and legumes, and aloe vera), seaweed, and nut and seed pulps and preparations (e.g. vegetable desserts and sauces, candied vegetables) other than food category 04.2.2.5

 250 mg/kg Note 17,Note 161
14.1.3.2

Vegetable nectar

 400 mg/kg Note 17,Note 161
14.1.4

Water-based flavoured drinks, including "sport," "energy," or "electrolyte" drinks and particulated drinks

 350 mg/kg Note 17,Note 127

From www.fao.org

Computed Descriptors

Download SDF
2D Structure
CID8752
IUPAC Namecalcium;N-cyclohexylsulfamate
InChIInChI=1S/2C6H13NO3S.Ca/c2*8-11(9,10)7-6-4-2-1-3-5-6;/h2*6-7H,1-5H2,(H,8,9,10);/q;;+2/p-2
InChI KeyUKLJMHXGZUJRTL-UHFFFAOYSA-L
Canonical SMILESC1CCC(CC1)NS(=O)(=O)[O-].C1CCC(CC1)NS(=O)(=O)[O-].[Ca+2]
Molecular FormulaC12H24CaN2O6S2
Wikipediacalcium cyclamate anhydrous

From Pubchem

Computed Properties

Property Name Property Value
Molecular Weight396.53
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count2
Complexity187.0
CACTVS Substructure Key Fingerprint A A A D c e B z O A B g A A g A A A A A A A A A A A A A A A A A A A A w Y A A A A A A A A A A A A A A A H A A Q Q A A A C C j B A A Q A A A B A A A A A A A A A A D A A A A A A A A A A A I A A A A A A A A I A g A A A A A A A E A A A A A E Q A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A = =
Topological Polar Surface Area155.0
Monoisotopic Mass396.07
Exact Mass396.07
Compound Is CanonicalizedTrue
Formal Charge0
Heavy Atom Count23
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Isotope Atom Count0
Covalently-Bonded Unit Count3

From Pubchem

Taxonomic Classification

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassSulfamic acid derivatives
SubclassCyclamates
Intermediate Tree NodesNot available
Direct ParentCyclamates
Alternative Parents
Molecular FrameworkNot available
SubstituentsCyclamic_acid_derivative - Sulfuric acid monoamide - Organic sulfuric acid or derivatives - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic salt - Organonitrogen compound - Aliphatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as cyclamates. These are compounds containing a cyclohexylsulfamic acid moiety.

From ClassyFire