RIBOFLAVIN 5'-PHOSPHATE SODIUM

Relevant Data

Food Additives Approved in the United States

General Information

Synonyms: VITAMIN B2 PHOSPHATE ESTER MONOSODIUM SALT
Chemical Names: MONOSODIUM SALT OF 5'-MONOPHOSPHATE ESTER OF RIBOFLAVIN
CAS number: 130-40-5
INS:

101(ii)
Functional Class: Food Additives
COLOUR

From apps.who.int

Evaluations

Evaluation year: 1981
ADI: 0-0.5 mg/kg bw
Meeting: 25
Specs Code: R (1987)
Comments: Group ADI for riboflavin and riboflanin-5'-phosphate, expressed as riboflavin
Report: TRS 669-JECFA 25/20
Tox Monograph: FAS 16-JECFA 25/181
Specification: COMPENDIUM ADDENDUM 10/FNP 52 Add.10/34 (METALS LIMITS) (2002). R; FAO JECFA Monographs 1 vol.3/251

From apps.who.int

GSFA Provisions for RIBOFLAVIN 5'-PHOSPHATE SODIUM

Number Food Category Max Level Notes
05.2

Confectionery including hard and soft candy, nougats, etc. other than food categories 05.1, 05.3 and 05.4

 1,000 mg/kg Note XS309R
09.2.4.1

Cooked fish and fish products

 300 mg/kg Note 95
08.4

Edible casings (e.g. sausage casings)

 1,000 mg/kg Note 16
09.3.1

Fish and fish products, including mollusks, crustaceans, and echinoderms, marinated and/or in jelly

 300 mg/kg Note 16
09.3.2

Fish and fish products, including mollusks, crustaceans, and echinoderms, pickled and/or in brine

 300 mg/kg Note 16
01.1.4

Flavoured fluid milk drinks

 300 mg/kg Note 52
10.1

Fresh eggs

 300 mg/kg Note 4
09.2.4.3

Fried fish and fish products, including mollusks, crustaceans, and echinoderms

 300 mg/kg Note 16
09.2.2

Frozen battered fish, fish fillets, and fish products, including mollusks, crustaceans, and echinoderms

 300 mg/kg Note XS166,Note 16
09.2.1

Frozen fish, fish fillets, and fish products, including mollusks, crustaceans, and echinoderms

 1,000 mg/kg Note XS315,Note XS165,Note XS95,Note XS36,Note 95,Note XS292,Note XS92,Note XS312,Note XS191,Note XS190
09.2.3

Frozen minced and creamed fish products, including mollusks, crustaceans, and echinoderms

 300 mg/kg Note 16
04.1.2.8

Fruit preparations, including pulp, purees, fruit toppings and coconut milk

 300 mg/kg Note 182
09.4

Fully preserved, including canned or fermented fish and fish products, including mollusks, crustaceans, and echinoderms

 500 mg/kg Note 95
06.4.3

Pre-cooked pastas and noodles and like products

 300 mg/kg Note 153
08.3

Processed comminuted meat, poultry, and game products

 1,000 mg/kg Note XS89,Note XS88,Note XS98,Note 16
08.2

Processed meat, poultry, and game products in whole pieces or cuts

 1,000 mg/kg Note XS97,Note XS96,Note 16
09.2.5

Smoked, dried, fermented, and/or salted fish and fish products, including mollusks, crustaceans, and echinoderms

 300 mg/kg Note XS311,Note 22
12.5

Soups and broths

 200 mg/kg Note 344
04.1.1.2

Surface-treated fresh fruit

 300 mg/kg Note 4,Note 16
04.2.1.2

Surface-treated fresh vegetables (including mushrooms and fungi, roots and tubers, pulses and legumes, and aloe vera), seaweeds, and nuts and seeds

 300 mg/kg Note 4,Note 16
04.2.2.6

Vegetable (including mushrooms and fungi, roots and tubers, pulses and legumes, and aloe vera), seaweed, and nut and seed pulps and preparations (e.g. vegetable desserts and sauces, candied vegetables) other than food category 04.2.2.5

 300 mg/kg Note 92

From www.fao.org

Computed Descriptors

Download SDF
2D Structure
CID23666409
IUPAC Namesodium;[(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
InChIInChI=1S/C17H21N4O9P.Na/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);/q;+1/p-1/t11-,12+,14-;/m0./s1
InChI KeyOHSHFZJLPYLRIP-BMZHGHOISA-M
Canonical SMILESCC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)[O-])O)O)O.[Na+]
Molecular FormulaC17H20N4NaO9P
Wikipediaflavin mononucleotide

From Pubchem

Computed Properties

Property Name Property Value
Molecular Weight478.33
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Complexity856.0
CACTVS Substructure Key Fingerprint A A A D c e B 7 v C I A A A A A A A A A A A A A A A A A A A A A A A A w Q I A A A A A A A A C B A A A A H g A Q C C A A D B z h m A Y z w I P A A x C o Q y d y d I C C A A E h A g A B i A E o d I i L c C r A 2 Z G U Y A h n h S L Z y A f w k I I O i A A A Q A A Q A C A Q A A C A A C A A Q A A A A A A A A A = =
Topological Polar Surface Area204.0
Monoisotopic Mass478.087
Exact Mass478.087
Compound Is CanonicalizedTrue
Formal Charge0
Heavy Atom Count32
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Isotope Atom Count0
Covalently-Bonded Unit Count2

From Pubchem

Taxonomic Classification

KingdomOrganic compounds
SuperclassNucleosides, nucleotides, and analogues
ClassFlavin nucleotides
SubclassNot available
Intermediate Tree NodesNot available
Direct ParentFlavin nucleotides
Alternative Parents
Molecular FrameworkAromatic heteropolycyclic compounds
SubstituentsFlavin nucleotide - Flavin - Isoalloxazine - Diazanaphthalene - Quinoxaline - Pteridine - Pyrimidone - Phosphoric acid ester - Organic phosphoric acid derivative - Pyrazine - Pyrimidine - Benzenoid - Alkyl phosphate - Vinylogous amide - Heteroaromatic compound - Secondary alcohol - Lactam - Azacycle - Polyol - Organic alkali metal salt - Organoheterocyclic compound - Organic nitrogen compound - Alcohol - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic sodium salt - Organic oxygen compound - Organic salt - Organic zwitterion - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as flavin nucleotides. These are nucleotides containing a flavin moiety. Flavin is a compound that contains the tricyclic isoalloxazine ring system, which bears 2 oxo groups at the 2- and 4-positions.

From ClassyFire