SERINE PROTEASE (CHYMOTRYPSIN) FROM NOCARDIOPSIS PRASINA EXPRESSED IN BACILLUS LICHENIFORMIS
General Information
| Chemical Names: | chymotrypsin: (EC 3.4.21.1) |
| Functional Class: |
Food Additives ENZYME_PREPARATION |
From apps.who.int
Evaluations
| Evaluation year: | 2012 |
| ADI: | NOT SPECIFIED |
| Specs Code: | N |
| Comments: | Comparing the exposure estimate with the NOAEL from the 13-week study of oral toxicity in rats, the margin of exposure is approximately 350. The Committee allocated an ADI “not specified”b for serine protease (chymotrypsin) enzyme preparation from N. prasina expressed in the production strain B. licheniformis, used in the applications specified and in accordance with good manufacturing practice. |
| Report: | TRS 974 JECFA 76 |
| Tox Monograph: | FAS 67 JECFA 76 |
| Specification: | Compendium of food additive specifications. FAO JECFA Monographs 13, 2012 |
From apps.who.int