Main Reaction: alpha-acetohydroxybutyrate >> isoleucine

Reference: PubMed ID: 3045082
Authors: Chang YY, Cronan JE Jr
Title: Common ancestry of Escherichia coli pyruvate oxidase and the acetohydroxy acid synthases of the branched-chain amino acid biosynthetic pathway.
Published: 1988 Sep

alpha-acetohydroxybutyrate --> isoleucine