Main Reaction: L-Proline + 2-Oxoglutarate + O2 >> Succinate + CO2 + trans-4-Hydroxy-L-proline

Reference: PubMed ID: 8546682
Authors: Lawrence CC, Sobey WJ, Field RA, Baldwin JE, Schofield CJ
Title: Purification and initial characterization of proline 4-hydroxylase from Streptomyces griseoviridus P8648: a 2-oxoacid, ferrous-dependent dioxygenase involved in etamycin biosynthesis.
Published: 1996 Jan 1

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