Main Reaction: HCO3-+ Biotin + Acetyl-CoA >> Malonyl-CoA + Pi

Reference: PubMed ID: 21723339
Authors: Rathnasingh C, Raj SM, Lee Y, Catherine C, Ashok S, Park S
Title: Production of 3-hydroxypropionic acid via malonyl-CoA pathway using recombinant Escherichia coli strains.
Published: 2012 Feb 20

HCO3- + Biotin + Acetyl-CoA --> Malonyl-CoA + Pi