Main Reaction: Serine + 16:0-CoA >> 3-Keto-DHSph

Reference: PubMed ID: 22615416
Authors: Gorshkova I, Zhou T, Mathew B, Jacobson JR, Takekoshi D, Bhattacharya P, Smith B, Aydogan B, Weichselbaum RR, Natarajan V, Garcia JG, Berdyshev EV
Title: Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
Published: 2012 Aug

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