Main Reaction: glucose + NADPH >> sorbitol + NADP+

Reference: PubMed ID: 11114100
Authors: Chakrabarti S, Cukiernik M, Hileeto D, Evans T, Chen S
Title: Role of vasoactive factors in the pathogenesis of early changes in diabetic retinopathy.
Published: 2000 Nov-Dec

glucose + NADPH --> sorbitol + NADP