Main Reaction: 2alpha-ketoglutarate + NADPH + Lysine (LYS) + 4 NAD+ >> 2 Glutamate (GLU) + NADP+ + 2 CO2 + Acetoacetyl-CoA [8 steps] + 4 NADH

Reference: PubMed ID: 11120643
Authors: Lee K, Berthiaume F, Stephanopoulos GN, Yarmush DM, Yarmush ML
Title: Metabolic flux analysis of postburn hepatic hypermetabolism.
Published: 2000 Oct

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