Tryptophan synthase alpha chain

NameTryptophan synthase alpha chain
Synonyms
  • 4.2.1.20
Gene NametrpA
OrganismThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Amino acid sequence
>lcl|BSEQ0011224|Tryptophan synthase alpha chain
MTTLEAFAKARSEGRAALIPYLTAGFPSREGFLQAVEEVLPYADLLEIGLPYSDPLGDGP
VIQRASELALRKGMSVQGALELVREVRALTEKPLFLMTYLNPVLAWGPERFFGLFKQAGA
TGVILPDLPPDEDPGLVRLAQEIGLETVFLLAPTSTDARIATVVRHATGFVYAVSVTGVT
GMRERLPEEVKDLVRRIKARTALPVAVGFGVSGKATAAQAAVADGVVVGSALVRALEEGR
SLAPLLQEIRQGLQRLEANPGLKESSKKPLS
Number of residuesNone
Molecular Weight28936.25
Theoretical pI6.09
GO Classification
Functions
  • tryptophan synthase activity
Processes
Components
General FunctionTryptophan synthase activity
Specific FunctionThe alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
Transmembrane Regions
GenBank Protein ID
UniProtKB IDP16608
UniProtKB Entry Name
Cellular LocationNone
Gene sequence
>lcl|BSEQ0011225|Tryptophan synthase alpha chain (trpA)
GTGACCACCCTCGAGGCCTTCGCCAAGGCCCGGTCCGAGGGCCGGGCCGCCCTCATCCCT
TACCTCACCGCGGGCTTCCCCAGCCGGGAGGGCTTTTTGCAGGCGGTGGAGGAGGTCCTC
CCCTATGCCGACCTTCTGGAGATCGGCCTCCCCTACTCCGACCCCCTGGGGGACGGCCCC
GTGATCCAGCGGGCAAGCGAACTGGCCCTGAGGAAGGGGATGAGCGTCCAAGGCGCTTTG
GAGCTCGTCCGCGAGGTGCGCGCCCTCACGGAGAAACCCCTCTTCCTCATGACCTACCTG
AACCCCGTCCTGGCCTGGGGGCCGGAGCGCTTCTTCGGCCTCTTCAAGCAGGCGGGGGCC
ACGGGGGTGATCCTTCCCGACCTTCCCCCCGACGAGGACCCAGGCCTCGTGCGCCTCGCC
CAGGAGATCGGCCTGGAGACGGTCTTCCTTCTCGCCCCCACCTCCACGGACGCCCGCATC
GCCACCGTGGTCCGCCACGCCACGGGCTTCGTCTACGCCGTCTCCGTCACCGGGGTCACG
GGGATGCGGGAAAGGCTTCCCGAGGAGGTCAAGGACCTGGTGCGGCGCATCAAGGCCAGG
ACCGCCCTCCCCGTGGCCGTGGGCTTCGGGGTTTCCGGCAAGGCCACGGCCGCGCAGGCG
GCGGTGGCGGACGGGGTGGTGGTGGGAAGCGCCTTGGTCCGGGCCTTGGAGGAGGGGAGG
TCCCTTGCGCCCCTTCTCCAGGAGATCCGCCAGGGCCTCCAGCGCCTCGAGGCCAACCCC
GGCCTGAAGGAAAGCTCAAAGAAGCCGTTGTCCTGA
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC ID
Chromosome LocationNone
LocusNone
References
  1. Koyama Y, Furukawa K: Cloning and sequence analysis of tryptophan synthetase genes of an extreme thermophile, Thermus thermophilus HB27: plasmid transfer from replica-plated Escherichia coli recombinant colonies to competent T. thermophilus cells. J Bacteriol. 1990 Jun;172(6):3490-5. [2188962 ]
  2. Henne A, Bruggemann H, Raasch C, Wiezer A, Hartsch T, Liesegang H, Johann A, Lienard T, Gohl O, Martinez-Arias R, Jacobi C, Starkuviene V, Schlenczeck S, Dencker S, Huber R, Klenk HP, Kramer W, Merkl R, Gottschalk G, Fritz HJ: The genome sequence of the extreme thermophile Thermus thermophilus. Nat Biotechnol. 2004 May;22(5):547-53. Epub 2004 Apr 4. [15064768 ]

From www.t3db.ca