Nicotinate-nucleotide adenylyltransferase

NameNicotinate-nucleotide adenylyltransferase
Synonyms
  • 2.7.7.18
  • Deamido-NAD(+) diphosphorylase
  • Deamido-NAD(+) pyrophosphorylase
  • NaMN adenylyltransferase
  • Nicotinate mononucleotide adenylyltransferase
Gene NamenadD
OrganismShigella flexneri
Amino acid sequence
>lcl|BSEQ0011856|Nicotinate-nucleotide adenylyltransferase
MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSVQRKHML
ELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEY
ETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPEDLHLQPAGKIYLAETPWFNIS
ATIIRERLQNGESCEDLLPEPVLTYINQQGLYR
Number of residuesNone
Molecular Weight24527.75
Theoretical pI5.54
GO Classification
Functions
  • ATP binding
  • nicotinate-nucleotide adenylyltransferase activity
Processes
  • NAD biosynthetic process
Components
General FunctionNicotinate-nucleotide adenylyltransferase activity
Specific FunctionCatalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
Transmembrane Regions
GenBank Protein ID
UniProtKB IDP0A753
UniProtKB Entry Name
Cellular LocationNone
Gene sequence
>lcl|BSEQ0011857|Nicotinate-nucleotide adenylyltransferase (nadD)
ATGAAATCTTTACAGGCTCTGTTTGGCGGCACCTTTGATCCGGTGCACTATGGTCATCTA
AAACCCGTGGAAACGCTGGCGAATTTGATTGGTCTGACGCGGGTCACAATCATCCCTAAT
AATGTTCCTCCGCATCGTCCCCAGCCGGAAGCGAACAGCGTGCAGCGTAAACACATGCTT
GAACTGGCGATTGCCGACAAGCCATTATTTACTCTTGATGAACGCGAGCTAAAGCGCAAT
GCCCCCTCTTACACTGCGCAAACACTGAAAGAGTGGCGGCAGGAACAAGGACCGGACGTG
CCGCTGGCGTTTATTATTGGTCAGGATTCATTGCTGACCTTTCCGACCTGGTACGAATAC
GAAACGATACTCGACAATGCACATTTGATCGTCTGTCGGCGTCCAGGTTACCCACTTGAA
ATGGCGCAACCGCAATACCAGCAATGGCTGGAAGATCATTTGACACATAACCCGGAAGAT
CTTCACCTTCAGCCTGCCGGTAAAATTTATCTGGCTGAAACGCCGTGGTTTAACATCTCG
GCGACCATCATCCGCGAACGTTTGCAAAACGGTGAATCGTGTGAGGATTTATTGCCGGAA
CCGGTATTGACTTACATTAACCAACAAGGCTTGTATCGCTGA
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC ID
Chromosome LocationNone
LocusNone
References
  1. Jin Q, Yuan Z, Xu J, Wang Y, Shen Y, Lu W, Wang J, Liu H, Yang J, Yang F, Zhang X, Zhang J, Yang G, Wu H, Qu D, Dong J, Sun L, Xue Y, Zhao A, Gao Y, Zhu J, Kan B, Ding K, Chen S, Cheng H, Yao Z, He B, Chen R, Ma D, Qiang B, Wen Y, Hou Y, Yu J: Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res. 2002 Oct 15;30(20):4432-41. [12384590 ]
  2. Wei J, Goldberg MB, Burland V, Venkatesan MM, Deng W, Fournier G, Mayhew GF, Plunkett G 3rd, Rose DJ, Darling A, Mau B, Perna NT, Payne SM, Runyen-Janecky LJ, Zhou S, Schwartz DC, Blattner FR: Complete genome sequence and comparative genomics of Shigella flexneri serotype 2a strain 2457T. Infect Immun. 2003 May;71(5):2775-86. [12704152 ]

From www.t3db.ca