3-carboxy-cis,cis-muconate cycloisomerase

Name	3-carboxy-cis,cis-muconate cycloisomerase
Synonyms	3-carboxymuconate lactonizing enzyme 5.5.1.2 CMLE
Gene Name	pcaB
Organism	Pseudomonas putida
Amino acid sequence	>lcl\|BSEQ0006379\|3-carboxy-cis,cis-muconate cycloisomerase MTNQLFDAYFTAPAMREIFSDRGRLQGMLDFEAALARAEAAAGLVPHSAVAAIEAACKAE RYDVGALANAIATAGNSAIPLVKALGKVIASGVPEAERYVHLGATSQDAMDTGLVLQLRD ALDLIEADLGKLADTLSQQALKHADTPMVGRTWLQHATPVTLGMKLAGVLGALTRHRQRL QELGPPCWCCSSGGASGSLAALGSKAMPVAEALAEQLKLSLPEQPWHTQRDRLVEFASVL GLVAGSLGKFGRDVSLLMQTEAGEVFEPSAPGKGGSSTMPHKRNPVGAAVLIGAATRVPG LVSTLFAAMPQEHERSLGLWHAEWETLPDICCLVSGALRQAQVIAEGIEVDAARMRRNLD LTQGLVLAEAVSIVLARTLGRDRAHHLLEQCCQRAVAEQRHLRAVLGDDPQVSAELSAEE LD
Number of residues	None
Molecular Weight	44675.755
Theoretical pI	5.93
GO Classification	Functions 3-carboxy-cis,cis-muconate cycloisomerase activity Processes beta-ketoadipate pathway 3,4-dihydroxybenzoate catabolic process Components cytoplasm
General Function	3-carboxy-cis,cis-muconate cycloisomerase activity
Specific Function	Catalyzes an anti cycloisomerization.
Transmembrane Regions
GenBank Protein ID
UniProtKB ID	P32427
UniProtKB Entry Name
Cellular Location	Cytoplasm
Gene sequence	>lcl\|BSEQ0006378\|1224 bp ATGACCAACCAACTGTTCGACGCCTACTTCACCGCGCCGGCCATGCGCGAGATTTTCTCC GACCGTGGCCGCTTGCAGGGCATGCTCGATTTCGAAGCCGCGCTGGCCCGTGCCGAAGCT GCTGCGGGGCTGGTCCCGCACAGCGCCGTGGCCGCCATCGAGGCGGCATGCAAGGCCGAG CGCTATGACGTGGGGGCGCTGGCCAATGCCATCGCAACCGCTGGCAACTCGGCAATCCCG CTGGTGAAGGCGTTGGGCAAGGTGATTGCCAGTGGCGTGCCCGAGGCCGAGCGCTATGTG CACTTGGGCGCCACCAGCCAGGACGCGATGGACACCGGTCTGGTGTTGCAGTTGCGCGAT GCCCTCGACCTGATCGAAGCGGACCTGGGCAAACTGGCCGATACCCTGTCGCAGCAGGCA TTGAAGCACGCCGATACGCCAATGGTGGGCCGCACCTGGCTGCAACACGCTACCCCGGTG ACCCTGGGCATGAAACTGGCTGGCGTGCTGGGGGCATTGACCCGCCACCGTCAGCGCCTG CAAGAGCTCGGCCCGCCCTGTTGGTGCTGCAGTTCCGGCGGCGCCTCGGGCAGCCTGGCC GCTCTGGGCAGCAAGGCGATGCCGGTGGCCGAGGCCCTGGCCGAGCAACTGAAGCTGAGC CTGCCCGAGCAACCCTGGCACACCCAGCGTGATCGCCTGGTGGAGTTTGCCTCGGTGCTG GGCCTTGTGGCCGGCAGCCTGGGCAAGTTCGGCCGCGATGTCAGCCTGCTGATGCAAACC GAGGCGGGGGAGGTGTTCGAGCCTTCTGCACCAGGCAAGGGCGGCTCCTCGACCATGCCA CACAAGCGCAACCCGGTGGGCGCTGCGGTGCTGATCGGTGCCGCGACTCGCGTGCCGGGG CTGGTATCGACGCTGTTCGCCGCCATGCCCCAGGAGCACGAGCGCAGCCTGGGCCTGTGG CATGCCGAATGGGAAACCCTCCCGGACATCTGCTGCCTGGTCTCCGGCGCGCTGCGCCAG GCCCAGGTCATTGCCGAGGGCATTGAAGTAGACGCAGCGCGCATGCGCCGTAACCTCGAC CTGACCCAAGGGCTGGTGCTGGCAGAAGCGGTGAGTATCGTCCTGGCCCGAACGCCTGGG CCGCGACCGTGCCCACCACTTGCTGGAGCAATGCTGCCAGCGAGCCGTGGCCGAACAGCG GCACCTGCGTGCGGTGCTGGGTGA
GenBank Gene ID
GeneCard ID	None
GenAtlas ID
HGNC ID
Chromosome Location	None
Locus	None
References	Williams SE, Woolridge EM, Ransom SC, Landro JA, Babbitt PC, Kozarich JW: 3-Carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida is homologous to the class II fumarase family: a new reaction in the evolution of a mechanistic motif. Biochemistry. 1992 Oct 13;31(40):9768-76. [1390752 ]

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