1-aminocyclopropane-1-carboxylate deaminase

Name	1-aminocyclopropane-1-carboxylate deaminase
Synonyms	3.5.99.7 ACC deaminase
Gene Name	acdS
Organism	Pseudomonas sp. (strain ACP)
Amino acid sequence	>lcl\|BSEQ0016407\|1-aminocyclopropane-1-carboxylate deaminase MNLQRFPRYPLTFGPTPIQPLARLSKHLGGKVHLYAKREDCNSGLAFGGNKTRKLEYLIP EALAQGCDTLVSIGGIQSNQTRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIQMSR ILGADVRLVPDGFDIGFRRSWEDALESVRAAGGKPYAIPAGCSDHPLGGLGFVGFAEEVR AQEAELGFKFDYVVVCSVTGSTQAGMVVGFAADGRADRVIGVDASAKPAQTREQITRIAR QTAEKVGLERDIMRADVVLDERFAGPEYGLPNEGTLEAIRLCARTEGMLTDPVYEGKSMH GMIEMVRNGEFPEGSRVLYAHLGGVPALNGYSFIFRDG
Number of residues	None
Molecular Weight	36671.515
Theoretical pI	6.52
GO Classification	Functions pyridoxal phosphate binding 1-aminocyclopropane-1-carboxylate deaminase activity Processes 1-aminocyclopropane-1-carboxylate metabolic process amine catabolic process Components
General Function	Pyridoxal phosphate binding
Specific Function	Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.
Transmembrane Regions
GenBank Protein ID
UniProtKB ID	Q00740
UniProtKB Entry Name
Cellular Location	Cytoplasmic
Gene sequence	>lcl\|BSEQ0002734\|1017 bp ATGAACCTGCAACGATTCCCTCGTTACCCGCTGACTTTCGGGCCGACGCCAATCCAACCG CTAGCGCGTCTGAGCAAGCACCTCGGCGGCAAAGTGCATCTGTATGCGAAACGCGAAGAC TGCAACAGCGGCCTGGCGTTCGGTGGCAACAAGACACGCAAGCTCGAATATCTGATCCCT GAAGCGCTTGCTCAGGGTTGCGACACGCTCGTGTCGATCGGCGGCATTCAGTCGAACCAG ACGCGCCAGGTGGCGGCCGTGGCGGCTCATCTGGGCATGAAGTGCGTGCTGGTGCAGGAG AACTGGGTCAACTATTCGGACGCAGTCTACGACCGCGTCGGCAACATCCAGATGTCGCGC ATTCTCGGCGCCGATGTTCGCCTCGTGCCCGACGGCTTCGACATCGGTTTTCGCAGGAGC TGGGAGGATGCGCTGGAAAGCGTGCGGGCGGCCGGCGGCAAGCCGTATGCGATTCCGGCA GGCTGCTCGGATCACCCGCTCGGCGGCCTGGGTTTCGTCGGCTTCGCGGAGGAGGTGCGG GCGCAGGAAGCCGAATTGGGCTTCAAATTCGACTATGTCGTCGTGTGTTCCGTGACCGGC AGCACGCAGGCCGGCATGGTGGTGGGCTTCGCCGCTGACGGCCGCGCCGATCGCGTGATC GGCGTCGACGCTTCGGCCAAACCCGCGCAGACGCGCGAGCAGATCACCCGCATCGCGAGA CAGACCGCGGAGAAAGTCGGCCTGGAGCGCGATATCATGCGGGCCGACGTGGTGCTCGAC GAGCGCTTCGCGGGTCCGGAATACGGATTGCCGAACGAAGGCACGCTGGAAGCGATCCGC TTGTGCGCGCGCACGGAGGGCATGCTGACCGATCCCGTCTACGAAGGCAAATCGATGCAC GGCATGATCGAAATGGTGCGCAACGGCGAATTTCCGGAAGGCTCGCGCGTGCTGTATGCG CACCTCGGCGGGGTGCCGGCGTTGAACGGCTACAGCTTTATCTTCCGAGACGGCTGA
GenBank Gene ID
GeneCard ID	None
GenAtlas ID
HGNC ID
Chromosome Location	None
Locus	None
References	Sheehy RE, Honma M, Yamada M, Sasaki T, Martineau B, Hiatt WR: Isolation, sequence, and expression in Escherichia coli of the Pseudomonas sp. strain ACP gene encoding 1-aminocyclopropane-1-carboxylate deaminase. J Bacteriol. 1991 Sep;173(17):5260-5. [1885510 ]

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