UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase

NameUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
Synonyms
  • 3.5.1.-
  • envA
  • UDP-3-O-acyl-GlcNAc deacetylase
Gene NamelpxC
OrganismAquifex aeolicus (strain VF5)
Amino acid sequence
>lcl|BSEQ0010930|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
MGLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHST
DLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNRE
IDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTF
CFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGS
PVKGKFYSFRGGHSLNVKLVKELAKKQKLTRDLPHLPSVQAL
Number of residuesNone
Molecular Weight32144.765
Theoretical pI6.75
GO Classification
Functions
  • UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Processes
  • lipid A biosynthetic process
Components
General FunctionUdp-3-o-[3-hydroxymyristoyl] n-acetylglucosamine deacetylase activity
Specific FunctionInvolved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
Transmembrane Regions
GenBank Protein ID
UniProtKB IDO67648
UniProtKB Entry Name
Cellular LocationCytoplasmic
Gene sequence
>lcl|BSEQ0010931|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (lpxC)
ATGGGATTAGAAAAGACGGTTAAAGAGAAATTAAGCTTTGAGGGTGTCGGTATACACACA
GGTGAATACTCAAAATTAATCATACATCCCGAAAAAGAAGGAACAGGAATCAGGTTTTTC
AAGAACGGAGTTTACATACCCGCAAGACATGAGTTCGTCGTTCACACAAATCACTCCACG
GATTTAGGCTTTAAAGGGCAAAGAATAAAAACGGTTGAACACATACTTTCCGTTCTCCAC
CTACTTGAGATAACAAACGTGACAATAGAAGTAATAGGGAACGAAATCCCTATACTTGAC
GGAAGTGGCTGGGAATTCTACGAAGCCATTAGGAAAAATATTCTCAATCAGAACAGAGAA
ATAGATTACTTTGTTGTAGAAGAACCCATTATCGTGGAAGACGAGGGAAGATTGATAAAG
GCAGAACCTTCAGACACGCTTGAGGTCACCTACGAGGGAGAATTTAAAAATTTCCTGGGA
AGGCAGAAGTTTACCTTTGTTGAAGGGAACGAAGAAGAAATAGTCCTTGCGCGGACTTTT
TGCTTTGACTGGGAAATAGAACACATTAAAAAAGTCGGTCTTGGGAAGGGAGGAAGCCTG
AAAAACACCCTCGTTCTCGGAAAGGATAAAGTGTACAACCCTGAAGGGCTAAGATACGAA
AACGAACCTGTAAGACACAAAGTGTTTGACCTTATAGGAGACCTTTACCTCCTTGGAAGT
CCCGTAAAAGGTAAGTTTTACTCCTTCAGGGGAGGGCACTCGCTCAACGTAAAACTCGTA
AAAGAGCTTGCAAAGAAACAAAAACTTACTCGTGATTTACCTCACCTTCCTTCCGTCCAA
GCTCTCTGA
GenBank Gene ID
GeneCard IDNone
GenAtlas ID
HGNC ID
Chromosome LocationNone
LocusNone
References
  1. Deckert G, Warren PV, Gaasterland T, Young WG, Lenox AL, Graham DE, Overbeek R, Snead MA, Keller M, Aujay M, Huber R, Feldman RA, Short JM, Olsen GJ, Swanson RV: The complete genome of the hyperthermophilic bacterium Aquifex aeolicus. Nature. 1998 Mar 26;392(6674):353-8. [9537320 ]

From www.t3db.ca