Xylose isomerase

Name	Xylose isomerase
Synonyms	5.3.1.5
Gene Name	xylA
Organism	Arthrobacter sp. (strain NRRL B3728)
Amino acid sequence	>lcl\|BSEQ0016355\|Xylose isomerase MSVQPTPADHFTFGLWTVGWTGADPFGVATRKNLDPVEAVHKLAELGAYGITFHDNDLIP FDATEAEREKILGDFNQALKDTGLKVPMVTTNLFSHPVFKDGGFTSNDRSIRRFALAKVL HNIDLAAEMGAETFVMWGGREGSEYDGSKDLAAALDRMREGVDTAAGYIKDKGYNLRIAL EPKPNEPRGDIFLPTVGHGLAFIEQLEHGDIVGLNPETGHEQMAGLNFTHGIAQALWAEK LFHIDLNGQRGIKYDQDLVFGHGDLTSAFFTVDLLENGFPNGGPKYTGPRHFDYKPSRTD GYDGVWDSAKANMSMYLLLKERALAFRADPEVQEAMKTSGVFELGETTLNAGESAADLMN DSASFAGFDAEAAAERNFAFIRLNQLAIEHLLGSR
Number of residues	None
Molecular Weight	43291.15
Theoretical pI	4.73
GO Classification	Functions xylose isomerase activity magnesium ion binding Processes pentose-phosphate shunt D-xylose metabolic process Components cytoplasm
General Function	Xylose isomerase activity
Specific Function	None
Transmembrane Regions
GenBank Protein ID
UniProtKB ID	P12070
UniProtKB Entry Name
Cellular Location	Cytoplasm
Gene sequence	>lcl\|BSEQ0002428\|1188 bp ATGAGCGTTCAGCCGACCCCTGCAGACCACTTCACCTTTGGCCTCTGGACCGTAGGATGG ACCGGCGCCGACCCATTCGGTGTCGCCACCCGCAAGAACCTGGACCCGGTAGAAGCCGTC CACAAGCTGGCCGAGCTCGGCGCCTACGGCATCACCTTCCACGACAATGACCTGATTCCT TTTGACGCCACCGAGGCAGAGCGCGAAAAGATCCTTGGTGACTTCAACCAGGCGCTGAAG GACACCGGCCTGAAGGTCCCAATGGTGACCACCAACCTGTTCAGCCACCCGGTCTTCAAG GACGGCGGCTTCACCTCTAACGACCGCTCGATCCGTCGTTTTGCACTGGCTAAGGTCCTG CACAACATCGACTTGGCAGCCGAGATGGGCGCCGAAACCTTCGTCATGTGGGGCGGGCGC GAAGGCAGCGAATACGACGGTTCCAAGGACCTGGCCGCAGCACTTGATCGCATGCGCGAA GGCGTGGACACGGCAGCTGGCTACATCAAGGACAAGGGTTACAACCTGCGCATCGCGCTG GAGCCAAAGCCAAATGAACCACGCGGCGACATCTTCCTGCCTACCGTCGGCCACGGCCTG GCCTTCATCGAGCAGCTGGAGCACGGCGACATCGTCGGCCTGAACCCAGAAACCGGCCAC GAGCAGATGGCCGGCCTGAACTTCACCCACGGCATCGCTCAGGCACTGTGGGCCGAGAAG CTGTTCCACATTGACCTCAACGGCCAGCGCGGCATCAAGTACGACCAGGACCTGGTCTTC GGCCACGGCGATCTGACCAGCGCGTTCTTCACCGTAGACCTGCTGGAAAACGGCTTCCCT AACGGCGGACCAAAGTACACCGGCCCACGCCACTTCGACTACAAGCCATCGCGCACCGAC GGCTACGACGGCGTGTGGGACTCGGCCAAGGCCAACATGTCCATGTACCTGCTGCTCAAG GAACGTGCCCTGGCCTTCCGTGCGGATCCAGAGGTACAGGAAGCCATGAAGACCTCGGGC GTCTTCGAACTGGGCGAAACCACCCTGAACGCCGGGGAAAGCGCAGCGGATCTGATGAAT GATTCCGCGAGCTTCGCAGGCTTTGACGCCGAGGCCGCCGCAGAGCGCAACTTCGCGTTC ATCCGCCTGAACCAGCTGGCCATCGAGCACCTGCTCGGCTCCCGCTAA
GenBank Gene ID
GeneCard ID	None
GenAtlas ID
HGNC ID
Chromosome Location	None
Locus	None
References	Loviny-Anderton T, Shaw PC, Shin MK, Hartley BS: D-Xylose (D-glucose) isomerase from Arthrobacter strain N.R.R.L. B3728. Gene cloning, sequence and expression. Biochem J. 1991 Jul 1;277 ( Pt 1):263-71. [1854339 ] Smith CA, Rangarajan M, Hartley BS: D-Xylose (D-glucose) isomerase from Arthrobacter strain N.R.R.L. B3728. Purification and properties. Biochem J. 1991 Jul 1;277 ( Pt 1):255-61. [1854338 ] Collyer CA, Henrick K, Blow DM: Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed by a 1,2-hydride shift. J Mol Biol. 1990 Mar 5;212(1):211-35. [2319597 ] Henrick K, Collyer CA, Blow DM: Structures of D-xylose isomerase from Arthrobacter strain B3728 containing the inhibitors xylitol and D-sorbitol at 2.5 A and 2.3 A resolution, respectively. J Mol Biol. 1989 Jul 5;208(1):129-57. [2769749 ] Henrick K, Blow DM, Carrell HL, Glusker JP: Comparison of backbone structures of glucose isomerase from Streptomyces and Arthrobacter. Protein Eng. 1987 Dec;1(6):467-9. [3508294 ]

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